Unique ID issued by UMIN | UMIN000020389 |
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Receipt number | R000023543 |
Scientific Title | Clinical trial of efficacy for tocilizumab in systemic sclerosis and sclerodermatous chronic GVHD |
Date of disclosure of the study information | 2016/01/06 |
Last modified on | 2019/06/17 19:41:36 |
Clinical trial of efficacy for tocilizumab in systemic sclerosis and sclerodermatous chronic GVHD
Clinical trial of efficacy for tocilizumab in systemic sclerosis and sclerodermatous chronic GVHD
Clinical trial of efficacy for tocilizumab in systemic sclerosis and sclerodermatous chronic GVHD
Clinical trial of efficacy for tocilizumab in systemic sclerosis and sclerodermatous chronic GVHD
Japan |
The patients with systemic sclerosis or sclerodermatous chronic GVHD.
Clinical immunology |
Others
NO
To whether tocilizumab improves the patients with systemic sclerosis or sclerodermatous chronic GVHD.
Safety,Efficacy
Evaluate skin score at 0, 1, 4, 8, 12, 16, 20, 24 weeks after treatment.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
treatment with tocilizumab
duration: 20 weeks
dosage: 8mg/kg
times: 6 times
Frequency: every 4 weeks
20 | years-old | <= |
Not applicable |
Male and Female
There is no natural remission of skin sclerosis.
1.Patients with a history of shock or hypersensitivity to this drug.
2.Patients who are complicated by infectious diseases.
3.Patients with a history of myocardial infarction or unstable angina.
4.Patients with reduced severe bone marrow function.
5.Women who may be pregnant or pregnant.
6.Lactating women
5
1st name | |
Middle name | |
Last name | Kazuhiko Takehara |
Kanazawa University Hospital
Dermatology
13-1 takaramachi, kanazawa
0762652343
takehara@med.m.kanazawa-u.ac.jp
1st name | |
Middle name | |
Last name | Takashi Matsushita |
Kanazawa University Hospital
Dermatology
13-1 takaramachi, kanazawa
0762652343
t-matsushita@med.kanazawa-u.ac.jp
Kanazawa University Hospital, Department of dermatology
none
Self funding
NO
2016 | Year | 01 | Month | 06 | Day |
Unpublished
Terminated
2015 | Year | 09 | Month | 01 | Day |
2018 | Year | 06 | Month | 29 | Day |
2015 | Year | 10 | Month | 01 | Day |
2018 | Year | 06 | Month | 29 | Day |
2015 | Year | 12 | Month | 28 | Day |
2019 | Year | 06 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023543
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