Unique ID issued by UMIN | UMIN000020795 |
---|---|
Receipt number | R000023672 |
Scientific Title | Colonization of Lactobacillus rhamnosus L8020 in the oral cavity after intake of L8020-containing tablets |
Date of disclosure of the study information | 2016/01/29 |
Last modified on | 2019/07/29 10:42:12 |
Colonization of Lactobacillus rhamnosus L8020 in the oral cavity after intake of L8020-containing tablets
Oral colonization of Lactobacillus rhamnosus L8020
Colonization of Lactobacillus rhamnosus L8020 in the oral cavity after intake of L8020-containing tablets
Oral colonization of Lactobacillus rhamnosus L8020
Japan |
Healthy adults
Dental medicine | Adult |
Others
NO
To investigate whether Lactobacillus rhamnosus L8020 can be detected in the oral cavity after the intake of tablets containing L8020
Efficacy
PCR detection for Lactobacillus in stimulated saliva 7 days before and 2, 7 and 14 days after intervention
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Prevention
Food |
Volunteers ingest three L8020-containing tablets everyday after lunch for two weeks
20 | years-old | <= |
100 | years-old | >= |
Male and Female
1. Healthy adult without dental caries, gingivitis and periodontal disease
2. Subject who will be able to prohibit foods with lactic acid bacteria, xylitol chewing gum and other tablets during experiment period
3. Subject who provide written informed consents
1. Subject with allergy to dairy products
2. Subject with a history of antibiotic treatment within a month before experiment
3. Subject who may receive treatments of topical fluoride or povidone-iodine during experiment period
50
1st name | |
Middle name | |
Last name | Hiroki Nikawa |
Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University
Department of Oral Biology & Engineering
1-2-3 Kasumi, Minami-ku, Hiroshima
082-257-5797
hirocky@hiroshima-u.ac.jp
1st name | |
Middle name | |
Last name | Tsuyoshi Taji |
Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University
Department of Oral Biology & Engineering
1-2-3 Kasumi, Minami-ku, Hiroshima
082-257-5797
taji@hiroshima-u.ac.jp
Department of Oral Biology & Engineering, Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University
Grants-in-aid for Scientific Research
NO
2016 | Year | 01 | Month | 29 | Day |
Unpublished
Completed
2016 | Year | 01 | Month | 29 | Day |
2017 | Year | 03 | Month | 15 | Day |
2016 | Year | 03 | Month | 01 | Day |
2018 | Year | 03 | Month | 31 | Day |
2018 | Year | 11 | Month | 05 | Day |
2016 | Year | 01 | Month | 29 | Day |
2019 | Year | 07 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023672
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |