Unique ID issued by UMIN | UMIN000020537 |
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Receipt number | R000023715 |
Scientific Title | Therapeutic efficacy and safety of telmisartan in patients with non-alcoholic fatty liver disease (NAFLD) and hypertension: exploratory research |
Date of disclosure of the study information | 2016/01/12 |
Last modified on | 2016/01/12 20:49:27 |
Therapeutic efficacy and safety of telmisartan in patients with non-alcoholic fatty liver disease (NAFLD) and hypertension: exploratory research
Efficacy and safety of telmisartan in patients with NAFLD and hypertension
Therapeutic efficacy and safety of telmisartan in patients with non-alcoholic fatty liver disease (NAFLD) and hypertension: exploratory research
Efficacy and safety of telmisartan in patients with NAFLD and hypertension
Japan |
Non-alcoholic fatty liver disease and hypertension
Medicine in general | Hepato-biliary-pancreatic medicine | Endocrinology and Metabolism |
Others
NO
To investigate the efficacy and safety of telmisartan for liver dysfunction in patients with non-alcoholic fatty liver disease and hypertension.
Safety,Efficacy
The change in the value of liver fibrosis marker between baseline and after 12 months of treatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
telmisartan (20 to 80 mg daily)
20 | years-old | <= |
Not applicable |
Male and Female
(1) ALT >= 30 IU/L without excess alcohol consumption
(2) Controlled attenuation parameter (CAP)>= 250 dB/m
(3) Clinic blood pressure >= 130/85 mmHg
(4) Written informed consent
(1) Treatment histody of ARB, ACE inhibitor, renin inhibitor, or thiazolidine
(2) History of hepatic disease, such as chronic hepatitis C or concurrent active hepatitis B (serum positive for hepatitis B surface antigen), autoimmune hepatitis, or primary biliary cirrhosis (PBC)
(3) Secondary hypertension
(4) History of allergy for telmisartan
(5) Pregnancy or lactation in women
(6) Inadequacy for this therapy
50
1st name | |
Middle name | |
Last name | Norihiro Furusyo |
Kyushu University Hospital
Department of General Internal Medicine
3-1-1, Maidashi, Higashi-ku, Fukuoka
092-642-5909
furusyo@gim.med.kyushu-u.ac.jp
1st name | |
Middle name | |
Last name | Motohiro Shimizu |
Kyushu University Hospital
Department of General Internal Medicine
3-1-1, Maidashi, Higashi-ku, Fukuoka
092-642-5909
smotohir@gim.med.kyushu-u.ac.jp
Department of General Internal Medicine, Kyushu University Hospital
None
Self funding
NO
2016 | Year | 01 | Month | 12 | Day |
Unpublished
Open public recruiting
2013 | Year | 10 | Month | 03 | Day |
2013 | Year | 11 | Month | 01 | Day |
2016 | Year | 01 | Month | 12 | Day |
2016 | Year | 01 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023715
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