Unique ID issued by UMIN | UMIN000020580 |
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Receipt number | R000023758 |
Scientific Title | Pilot study of tranilast for cardiomyopathy of muscular dystrophy |
Date of disclosure of the study information | 2016/01/20 |
Last modified on | 2017/01/15 09:42:11 |
Pilot study of tranilast for cardiomyopathy of muscular dystrophy
Pilot study of tranilast for cardiomyopathy of muscular dystrophy
Pilot study of tranilast for cardiomyopathy of muscular dystrophy
Pilot study of tranilast for cardiomyopathy of muscular dystrophy
Japan |
muscular dystrophy
Cardiology | Neurology |
Others
NO
To investigate the effects and safety of tranilast for cardiomyopathy of muscular dystrophy
Safety,Efficacy
Exploratory
Pragmatic
Not applicable
Left ventricular fractional shortening, Left ventricular dilated dimension (before, 1 month, 3 months)
Brain natriuretic peptide, cardiac troponin T, cardiac events (before, 1 month, 3 months)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Tranilast 300mg/day for three months (oral intake)
20 | years-old | <= |
Not applicable |
Male and Female
patients with muscular dystrophy
LVDd >=50%
LVFS < 20%
Patients with severe hepatic dysfunction, renal dysfunction, eosinophilia or any other conditions unsuitable for taking tranilast
2
1st name | |
Middle name | |
Last name | Tsuyoshi Matsumura |
National Hospital Organization Toneyama National Hospital
Neurology
Toneyama 5-1-1, Toyonaka, Osaka Japan
06-6853-2001
tmatsumura-toneyama@umin.org
1st name | |
Middle name | |
Last name | Tsuhoshi Matsumura |
National Hospital Organization Toneyama National Hospital
Neurology
Toneyama 5-1-1, Toyonaka, Osaka, Japan
06-6853-2001
tmatsumura-toneyama@umin.org
National Hospital Organization Toneyama National Hospital
National Hospital Organization Toneyama National Hospital
Self funding
National Cerebral and Cardiovascular Center
NO
国立病院機構刀根山病院
2016 | Year | 01 | Month | 20 | Day |
Unpublished
Two patients participated. BNP of both patients decreased after taking tranilast howevere no changes were found in UCG findings
Main results already published
2015 | Year | 08 | Month | 30 | Day |
2016 | Year | 01 | Month | 15 | Day |
2016 | Year | 05 | Month | 31 | Day |
2016 | Year | 06 | Month | 15 | Day |
2016 | Year | 07 | Month | 20 | Day |
2016 | Year | 09 | Month | 30 | Day |
2016 | Year | 01 | Month | 15 | Day |
2017 | Year | 01 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023758
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