Unique ID issued by UMIN | UMIN000020686 |
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Receipt number | R000023870 |
Scientific Title | Statin therapy for preeclampsia |
Date of disclosure of the study information | 2016/01/22 |
Last modified on | 2019/01/22 09:37:20 |
Statin therapy for preeclampsia
Statin therapy for preeclampsia
Statin therapy for preeclampsia
Statin therapy for preeclampsia
Japan |
preeclampsia
Obstetrics and Gynecology |
Others
NO
We examine whether statin inhibits oxidative stress in patients with preeclampsia.
Safety,Efficacy
Exploratory
maternal blood pressure, body weight, edema, liver function, kidney function, serum lipids, urinary protein
obstetric history, age, postpartum blood pressure, body weight, edema, liver function, kidney function, serum lipids, urinary protein until one week, extend the period of pregnancy, maternal serum soluble fms-like tyrosine kinase 1, maternal serum tumor necrosis factor alfa, maternal urine F2-Isoprostanes
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
administration of statin
Participants take pravastatin 10mg per day from diagnosis of preeclampsia to termination.
If participants have severe hyperlipemia, they take pravastatin 20mg per day.
non-administration of statin
20 | years-old | <= |
55 | years-old | >= |
Female
Patients who have preeclampsia with hyperlipemia.
Unconsented by patients or therapist
cyclosporin therapy
Past history of rhabdomyolysis
Past history of allergic reaction for statins
50
1st name | |
Middle name | |
Last name | Eiji Kondoh |
Kyoto University
Department of Gynecology and Obstetrics
54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto
075-751-3269
kondo@kuhp.kyoto-u.ac.jp
1st name | |
Middle name | |
Last name | Shingo Io |
Kyoto University
Department of Gynecology and Obstetrics
54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto
075-751-3269
shinio@kuhp.kyoto-u.ac.jp
Kyoto University Department of Gynecology and Obstetrics
Kyoto University Department of Gynecology and Obstetrics
Self funding
NO
京都大学医学部附属病院(京都府)
2016 | Year | 01 | Month | 22 | Day |
Unpublished
Open public recruiting
2016 | Year | 01 | Month | 22 | Day |
2016 | Year | 02 | Month | 10 | Day |
2016 | Year | 01 | Month | 21 | Day |
2019 | Year | 01 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023870
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