Unique ID issued by UMIN | UMIN000020923 |
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Receipt number | R000024106 |
Scientific Title | Effect of the SGLT2 inhibitor on basal energy expenditure in type 2 diabates mellitus |
Date of disclosure of the study information | 2016/02/08 |
Last modified on | 2018/08/12 18:21:24 |
Effect of the SGLT2 inhibitor on basal energy expenditure in type 2 diabates mellitus
SGLT2 inhibitor intervention study
Effect of the SGLT2 inhibitor on basal energy expenditure in type 2 diabates mellitus
SGLT2 inhibitor intervention study
Japan |
type 2 diabetes mellitus
Endocrinology and Metabolism |
Others
NO
We examine the influence of SGLT2 inhibitor on resting energy expenditure in type 2 diabetes mellitus.
Safety,Efficacy
resting energy expenditure of three months after taking medicine
body weight, respiration quotient and HbA1c of three months after taking medicine
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
The patient takes medicine with SGLT2 inhibitor of three months.
We prescribe only Empagliflozin in this study.
The dosage depends on therapy.
30 | years-old | <= |
84 | years-old | >= |
Male and Female
patients with type 2 diabetes mellitus
A patient with much active mass (exercise) in everyday life
A patient with after the third diabetic nephropathy
A patient with liver function abnormality
85 years or older
100
1st name | |
Middle name | |
Last name | Eitaro Nakashima |
Chubu Rosai Hospital, Japan Labour Health and Welfare Organization
DiaDiabetes & Endocrinology, Diabetes Center
1-10-6 Koumei Minato-ku Nagoya
052-652-5511
eitaro@med.nagoya-u.ac.jp
1st name | |
Middle name | |
Last name | Eitaro Nakashima |
Chubu Rosai Hospital, Japan Labour Health and Welfare Organization
DiaDiabetes & Endocrinology, Diabetes Center
1-10-6 Koumei Minato-ku Nagoya
052-652-5511
eitaro@med.nagoya-u.ac.jp
Nagoya University of Arts and Sciences
Nagoya University of Arts and Sciences
Other
NO
2016 | Year | 02 | Month | 08 | Day |
Unpublished
REE showed a decreasing trend of 1554(SD257)kcal/day and 1491(SD313)kcal/day before and after administration of SGLT 2 inhibitor, respectively, but it was not significant.
In addition, there was no significant difference in REE per body weight. Body weight and body fat mass decreased significantly, but skeletal muscle mass did not change significantly.
In conclusion, it was suggested that taking SGLT 2 inhibitor for 3 months may not affect REE.
Completed
2016 | Year | 01 | Month | 21 | Day |
2016 | Year | 01 | Month | 25 | Day |
2017 | Year | 12 | Month | 01 | Day |
2017 | Year | 12 | Month | 01 | Day |
2018 | Year | 03 | Month | 20 | Day |
2018 | Year | 03 | Month | 20 | Day |
2016 | Year | 02 | Month | 08 | Day |
2018 | Year | 08 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024106
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