Unique ID issued by UMIN | UMIN000021193 |
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Receipt number | R000024441 |
Scientific Title | Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma |
Date of disclosure of the study information | 2016/02/25 |
Last modified on | 2020/10/08 10:48:04 |
Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma
Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma
Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma
Study to evaluate the effectiveness and saftyof the mFOLFOX+bevacizumab combination therapy for bladder adenocarcinoma
Japan |
bladder adenocarcinoma
Urology |
Malignancy
NO
We perform mFOLFOX+bevacitumab therapy for patients with bladder adenocarcinoma and examine the effectiveness, safety.
Safety,Efficacy
response rate
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Administration of oxaliplatin, fluorouracil, levofolinate and bevacizumab
20 | years-old | <= |
80 | years-old | > |
Male and Female
1.The patients who have a diagnosis of a bladder adenocarcinoma histologically
2.The patients who are resistant to clinical trial S1+CDDP for the bladder adenocarcinoma and GD therapy of 2nd line for the urothelial carcinoma.
3.The patients who do not use bebacizumab
1.Case with serious myelosuppression
2.Case with the diarrhea (stools watery)
3.Case who had a serious infection
4.A large quantity of ascitic fluid, case with the pleural effusion
5.Case with serious heart disease or the anamnesis
6.The case that overall status worsens
7.Case with severe dysesthesia with the functional disorder or the dysesthesia
8.A pregnant woman or the case that may be pregnant and nursing mother
9.It is a case with a history of hypersensitivity for an ingredient including, levofolinate, fluorouracil, oxaliplatin and other platinum
5
1st name | Noriyasu |
Middle name | |
Last name | Kawai |
Nagoya City University Graduate School of Medical Sciences
Department of Nephro-urology
467-8601
1 Kawasumi, Mizuho-cho, Mizuho-ku,Nagoya, Japan
052-853-8266
n-kawai@med.nagoya-cu.ac.jp
1st name | Noriyasu |
Middle name | |
Last name | Kawai |
Nagoya City University Graduate School of Medical Sciences
Department of Nephro-urology
467-8601
1 Kawasumi, Mizuho-cho, Mizuho-ku,Nagoya, Japan
052-853-8266
n-kawai@med.nagoya-cu.ac.jp
Nagoya City University Hospital
none
Self funding
Nagoya City University Hospital Institutional Review Board
Kawasumi 1, Mizuho-cho,Mizuho-ku,Nagoya
052-858-7215
Clinical_research@med.nagoya-cu.ac.jp
NO
2016 | Year | 02 | Month | 25 | Day |
Unpublished
2
Completed
2014 | Year | 07 | Month | 01 | Day |
2014 | Year | 07 | Month | 31 | Day |
2014 | Year | 08 | Month | 15 | Day |
2019 | Year | 12 | Month | 31 | Day |
2016 | Year | 02 | Month | 25 | Day |
2020 | Year | 10 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024441
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