Unique ID issued by UMIN | UMIN000021380 |
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Receipt number | R000024454 |
Scientific Title | The effect of prasugrel on endothelial function in ischemic heart disease patients |
Date of disclosure of the study information | 2016/04/01 |
Last modified on | 2018/03/10 10:49:32 |
The effect of prasugrel on endothelial function in ischemic heart disease patients
The effect of prasugrel on endothelial function in ischemic heart disease patients
The effect of prasugrel on endothelial function in ischemic heart disease patients
The effect of prasugrel on endothelial function in ischemic heart disease patients
Japan |
ischemic heart disease
Cardiology |
Others
NO
To investigate whether prasugrel improves endothelial function
Efficacy
Reactive hyperemia index on 24 hours and 28 days after taking prasugrel compared with it on baseline
P2Y12 reaction units on 23 hours and 28 days after taking prasugrel compared with it on baseline
Observational
20 | years-old | <= |
80 | years-old | >= |
Male and Female
The inclusion criteria included the following: patients undergoing elective PCI; patients keeping taking aspirin; patients agreeing with this study after informed consent.
The exclusion criteria included the following: patients with unstable hemodynamics; patients underwent PCI or CABG within 4 weeks; patients in whom prasugrel is contraindicated; patients with severe hepatic dysfunction(liver cirrhosis, fulminant hepatitis, AST >100IU/L, ALT >100IU/L or Total bilirubin >3.0mg/dL); patients with severe renal dysfunction(eGFR <30mL/min); patients <50kg; patients with thorombocytepenia(platelet cell <100000/microL); patients with pregnancy or suspected pregnancy; patients administrated with anticoagulants(warfarin, dabigatran, rivaroxaban, apixaban or edoxaban); patients undergoing thrombolytic therapy; patinets administrated ticlopidine, cilostazol or clopidogrel; patients added or changed the drug for hypertension, dyslipidemia, diabetes or hyperuricemia within 2 weeks before agreement with this study; patients judged not eligible in this study.
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1st name | |
Middle name | |
Last name | Yoshio Kobayashi |
Chiba university graduate school of medicine
department of cardiovascular medicine
1-8-1, inohana, Chuo-ku, Chiba city, Japan
043-222-7171
yoshio.kobayashi@wonder.ocn.ne.jp
1st name | |
Middle name | |
Last name | Satoshi Tokimasa |
Chiba university graduate school of medicine
department of cardiovascular medicine
1-8-1, inohana, Chuo-ku, Chiba city, Japan
043-222-7171
YFD02270@nifty.com
department of cadiovascular medicine, Chiba university graduate school of medicine
none
Self funding
NO
2016 | Year | 04 | Month | 01 | Day |
Unpublished
Completed
2016 | Year | 04 | Month | 01 | Day |
2016 | Year | 04 | Month | 01 | Day |
2018 | Year | 01 | Month | 01 | Day |
2018 | Year | 03 | Month | 31 | Day |
every patients who meet the selection criteria in them admitted to our facility from April 2016 to March 2017 are included.
2016 | Year | 03 | Month | 07 | Day |
2018 | Year | 03 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024454
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