Unique ID issued by UMIN | UMIN000021308 |
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Receipt number | R000024576 |
Scientific Title | Elucidation of effects of acute endurance exercise on novel peptide hormone |
Date of disclosure of the study information | 2016/03/04 |
Last modified on | 2016/09/01 19:34:59 |
Elucidation of effects of acute endurance exercise on novel peptide hormone
Elucidation of effects of acute endurance exercise on novel peptide hormone
Elucidation of effects of acute endurance exercise on novel peptide hormone
Elucidation of effects of acute endurance exercise on novel peptide hormone
Japan |
Healthy males and females
Adult |
Others
NO
The purpose of this study was to evaluate whether acute endurance exercise modulates circulating peptide hormone level in healthy young and elderly subjects.
Efficacy
Effects of acute endurance exercise on circulating peptide hormone level
Effects of acute endurance exercise on blood biochemical parameters
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Educational,Counseling,Training
Other |
Young participants undertook an acute aerobic exercise using cycle ergometer. Exercise intensity was 70% of maximal oxygen uptake, and exercise duration was 30 minutes.
Elderly participants undertook an acute aerobic exercise using cycle ergometer. Exercise intensity was 70% of maximal oxygen uptake, and exercise duration was 30 minutes.
18 | years-old | <= |
Not applicable |
Male and Female
Healthy young subjects over 18 years old, and healthy elderly subjects over 60 years old
Subject who could not perform exercise and/or who have chronic diseases
30
1st name | |
Middle name | |
Last name | Mitsuru Higuchi |
Waseda University
Faculty of Sport Sciences
2-579-15 Mikajima, Tokorozawa, Saitama 359-1192
+81-4-2947-6745
mhiguchi@waseda.jp
1st name | |
Middle name | |
Last name | Hirokazu Taniguchi |
Waseda University
Graduate School of Sport Sciences
2-579-15 Mikajima, Tokorozawa, Saitama 359-1192
+81-4-2947-6745
hirokazu-t@akane.waseda.jp
Waseda University
Grant-in-Aid for JSPS Fellows. A Waseda University Grant. The Council for Science, Technology and Innovation, SIP, "Technologies for creating next-generation agriculture, forestry and fisheries".
Other
Japan
NO
早稲田大学 (Waseda University)
2016 | Year | 03 | Month | 04 | Day |
Published
http://www.ncbi.nlm.nih.gov/pubmed/27453549
Twenty-eight subjects participated in the experiment, of whom 13 were excluded mainly because of a serum FGF21 level below the limit of detection. Thus, data from seven young (age: 18-22 years) and eight elderly male subjects (age: 62-69 years) were analysed. Participants were asked to perform a cycling exercise for 30 min at 70% maximal oxygen uptake, following carbohydrate intake. Blood samples were collected pre-exercise and 0 min, 30 min, 1 h, 3 h and 24 h after the cessation of exercise.
Higher serum FGF21 was observed in the elderly subjects group throughout the experiment (P < 0.05). There was no significant increase in serum FGF21 levels after the cessation of exercise, whereas serum FGF21 levels were significantly lower 24 h after the exercise compared with those pre-exercise, 0 min, 30 min and 1 h after the cessation of exercise in both groups (P < 0.01).
Main results already published
2013 | Year | 10 | Month | 01 | Day |
2013 | Year | 10 | Month | 01 | Day |
2013 | Year | 12 | Month | 01 | Day |
2014 | Year | 03 | Month | 01 | Day |
2014 | Year | 07 | Month | 01 | Day |
2016 | Year | 12 | Month | 23 | Day |
2016 | Year | 03 | Month | 03 | Day |
2016 | Year | 09 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024576
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