Unique ID issued by UMIN | UMIN000021563 |
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Receipt number | R000024862 |
Scientific Title | A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation. |
Date of disclosure of the study information | 2016/03/25 |
Last modified on | 2018/11/16 16:28:57 |
A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation.
A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation.
A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation.
A randomized, double-blind, parallel-group study to evaluate the effect of alkalized lidocaine on hemodynamic changes during tracheal intubation.
Japan |
Patients who undergo surgeries under general anesthesia.
Anesthesiology |
Others
NO
The purpose of this study is to develop methods for prevention of intubation-induced adverse effects.
Safety,Efficacy
Changes in blood pressure and heart rate during tracheal intubation.
The degree of sore throat assessed by using a visual analogue scale (VAS, 0-100 mm) and hoarseness, dysphonea, nausea and vomitting are systematically evaluated as present or absent just after and at 15 minutes and 24 hours after extubation.
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
YES
NO
YES
3
Treatment
Medicine |
Laryngotrachal application of lidocaine before tracheal intubation.
Laryngotrachal application of alkalized lidocaine before tracheal intubation.
Laryngotrachal application of saline before tracheal intubation.
20 | years-old | <= |
Not applicable |
Male and Female
Adult patients (ASA physical status I or II) who required a tracheal intubation during general anesthesia.
Patients with anticipated difficult airway, patients who scheduled for surgery with nasotracheal intubation, patients who were pretreated with beta-blockers, patients who scheduled for surgery with epidural anesthesia, spinal anesthesia or nerve block in addition to general anesthesia, pregnant or lactating women, and paients who are allergic to local anesthetics.
60
1st name | |
Middle name | |
Last name | Kumiko Ishida |
Shinshu University School of Medicine
Department of anesthesiology and resuscitrogy
3-1-1 Asahi, Matsumoto, Nagano
0263372670
kumiko_m@shinshu-u.ac.jp
1st name | |
Middle name | |
Last name | Kumiko Ishida |
Shinshu University School of Medicine
Department of anesthesiology and resuscitrogy
3-1-1 Asahi, Matsumoto, Nagano
0263372670
kumiko_m@shinshu-u.ac.jp
Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine
Department of Anesthesiology and Resuscitology, Shinshu University School of Medicine
Other
NO
信州大学医学部附属病院(長野県)
2016 | Year | 03 | Month | 25 | Day |
Unpublished
Completed
2016 | Year | 03 | Month | 07 | Day |
2016 | Year | 03 | Month | 25 | Day |
2016 | Year | 03 | Month | 22 | Day |
2018 | Year | 11 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000024862
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