Unique ID issued by UMIN | UMIN000021688 |
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Receipt number | R000025018 |
Scientific Title | the evaluation of the appropriate dose of dexmedetomidine under Sedline which is the new monitoring for the degree of sedation |
Date of disclosure of the study information | 2016/03/31 |
Last modified on | 2018/12/10 16:09:49 |
the evaluation of the appropriate dose of dexmedetomidine under Sedline which is the new monitoring for the degree of sedation
the evaluation of the appropriate dose of dexmedetomidine under Sedline which is the new monitoring for the degree of sedation
the evaluation of the appropriate dose of dexmedetomidine under Sedline which is the new monitoring for the degree of sedation
the evaluation of the appropriate dose of dexmedetomidine under Sedline which is the new monitoring for the degree of sedation
Japan |
the patients proposed operation under local anesthesia
Anesthesiology | Operative medicine |
Others
NO
We compare the degree of sedation by middle dose of dexmedetomidine with minimum dose of it during using Sedline which is the monitoring for evaluation of the degree of sedation
Pharmacokinetics
the change of the degree of sedation, respiratory rate, oxygenation, systolic blood pressure and heart rate at every 15 minutes, and RASS score at the operation finished
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Dose comparison
2
Treatment
Medicine | Device,equipment |
low dose of dexmedetomidine group: 6 microgram/kg /hr dexmedetomidine was administered over a period of 10 minutes as a loading dose, and then maintenance infusion (0.2 microgram/kg/hr) was started.
middle dose of dexmedetomidine group: 6 microgram/kg /hr dexmedetomidine was administered over a period of 10 minutes as a loading dose, and then maintenance infusion (0.4 microgram/kg/hr) was started.
20 | years-old | <= |
60 | years-old | > |
Male and Female
the patients which has ASA PS I or II and proposed operation under local anesthesia
the patients who has difficulty in mutual understanding , has difficulty to get cooperation, has cardiovascular or respiratory or neurological complication
50
1st name | |
Middle name | |
Last name | Mitsutaka Edanaga |
Sapporo Medical University School of Medicine
Department of Anesthesiology
S1, W16, Chuo-ku, Sapporo, Hokkaido, Japan
011-688-9663
edanaka@sapmed.ac.jp
1st name | |
Middle name | |
Last name | Kouji Hamaya |
Sapporo Medical University School of Medicine
Hospital section
S1, W16, Chuo-ku, Sapporo, Hokkaido, Japan
011-611-2111
ko-hamaya-923@sapmed.ac.jp
Sapporo Medical University School of Medicine
Department of Anesthesiology, Sapporo Medical University School of Medicine
Self funding
NO
2016 | Year | 03 | Month | 31 | Day |
Unpublished
Terminated
2016 | Year | 02 | Month | 17 | Day |
2016 | Year | 04 | Month | 01 | Day |
2016 | Year | 03 | Month | 30 | Day |
2018 | Year | 12 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025018
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