Unique ID issued by UMIN | UMIN000021830 |
---|---|
Receipt number | R000025169 |
Scientific Title | Diagnosis of pulmonary lymphoma with BALF using molecular biological technique. |
Date of disclosure of the study information | 2016/04/07 |
Last modified on | 2022/04/12 22:24:07 |
Diagnosis of pulmonary lymphoma with BALF using molecular biological technique.
Diagnosis of pulmonary lymphoma with BALF.
Diagnosis of pulmonary lymphoma with BALF using molecular biological technique.
Diagnosis of pulmonary lymphoma with BALF.
Japan |
Pulmonary lymphoma
Pneumology |
Malignancy
NO
Establishmet of diagnositic method of pulmonary lymphoma using BALF with molecular biological technique
Efficacy
Exploratory
Not applicable
Sensitivity and Specificity of an assessment of BALF with molecular biological technique for pulmonary lymphoma.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1. Suspiscious of pulmonary lymphoma, and showing pulmonary infiltration in radiological examination, and will be recieved BAL for diagnosis.
2. Patients who are obtained with the prior written informed consent.
1. Cases who are judged unsuitableness by attending doctors.
2. Cases who can not be recieved bronchoscopic examination in safety.
100
1st name | Takashi |
Middle name | |
Last name | Kido |
University of Occupational and Environmental Health, Japan
Department of Respiratory Medicine
8078555
1-1, Iseigaoka, Yahatanishiku, Kitakyushu City, Fukuoka 807-8555, Japan
0936917453
t-kido@med.uoeh-u.ac.jp
1st name | Takashi |
Middle name | |
Last name | Kido |
University of Occupational and Environmental Health, Japan
Department of Respiratory Medicine
8078555
1-1, Iseigaoka, Yahatanishiku, Kitakyushu City, Fukuoka 807-8555, Japan
0936917453
t-kido@med.uoeh-u.ac.jp
Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
JSPS KAKENHI
Japanese Governmental office
Neurology,Respirology,Endocrinology and Metabolism. Department of Internal Medicine, Faculty of Medicine,University of Miyazaki Hospital.
Second Department of Internal Medicine, Nagasaki University Hospital.
Department of Respiratory Medicine, Fukuoka University.
Department of Respiratory Medicine, Wakamatsu Hospital of University of Occupational and Environmental Health, Japan.
Department of Respiratory Medicine, Kokura Memorial Hospital.
University of Occupational and Environmental Health, Japan
Iseigaoka, Yahatanishiku, Kitakyushu City, Fukuoka 807-8555, Japan
0936917453
t-kido@med.uoeh-u.ac.jp
NO
産業医科大学病院呼吸器内科(福岡県)
福岡大学病院呼吸器内科(福岡県)
長崎大学病院第2内科(長崎県)
宮崎大学病院第3内科(宮崎県)
産業医科大学若松病院(福岡県)
小倉記念病院(福岡県)
2016 | Year | 04 | Month | 07 | Day |
Published
doi: 10.1038/s41598-021-02861-4
39
IGH rearrangement detection for B-cell lymphoma diagnosis exhibited sensitivity and specificity of 88.9% and 90.0%, respectively. TCR rearrangements were not observed in patients with B-cell lymphomas. The presence of IGH rearrangements together with the absence of TCR rearrangements indicated 96.0% specificity for the diagnosis of B-cell lymphoma. The sensitivity and specificity of MALT1 translocations for diagnosing MALT lymphoma were 28.6% and 100%, respectively.
2022 | Year | 04 | Month | 12 | Day |
2021 | Year | 12 | Month | 06 | Day |
Patients suspected of having pulmonary lymphoma by attending physicians based on their clinical history, laboratory data, and chest high-resolution CT (HRCT) results and admitted to our hospitals between October 2013 to March 2018 were enrolled.
None.
In this study, we analyzed the feasibility of using BALF for combined detection of lymphocyte clonality based on IGH and TCR rearrangements as well as MALT1 translocations to diagnose pulmonary lymphomas.
Completed
2015 | Year | 08 | Month | 27 | Day |
2015 | Year | 08 | Month | 27 | Day |
2015 | Year | 08 | Month | 27 | Day |
2021 | Year | 08 | Month | 31 | Day |
To know the diagnostic value of an assessment of BALF with molecular biological technique for pulmonary lymphoma.
2016 | Year | 04 | Month | 07 | Day |
2022 | Year | 04 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025169
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |