Unique ID issued by UMIN | UMIN000022248 |
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Receipt number | R000025633 |
Scientific Title | The effects of sleep inducing drugs on circulation |
Date of disclosure of the study information | 2016/05/09 |
Last modified on | 2020/02/28 14:05:08 |
The effects of sleep inducing drugs on circulation
Sleep inducing drugs and circulation
The effects of sleep inducing drugs on circulation
Sleep inducing drugs and circulation
Japan |
healthy subjects
Anesthesiology | Adult |
Others
NO
We investigate the effects of sleep inducing drugs on cardiac and cerebral circulations.
Safety,Efficacy
cerebral autoregulation and baroreflex function at maximum drug concentration (Cmax) of sleep inducing drugs.
cerebral blood flow, arterial blood pressure, heart rate, stroke volume, respiratory condition, cerebral blood volume, cerebral metabolism, intracranial pressure.
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Active
2
Treatment
Medicine |
To be taken Suvorexant 20mg at bedtime. At least 7 days are allowed between interventions. the order of interventions are randomized in each subjects.
To be taken Brotizolam 0.25mg at bedtime. At least 7 days are allowed between interventions. the order of interventions are randomized in each subjects.
20 | years-old | <= |
60 | years-old | >= |
Male and Female
Healthy adult consented to participate in this study.
1) Not satisfy selection criteria noted above.
2) Volunteers having allergic factors to foods and/or drugs.
15
1st name | Ken-ichi |
Middle name | |
Last name | Iwasaki |
Nihon University School of Medicine
Division of Hygiene, Department of Social Medicine
173-8610
30-1, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo
03-3972-8111
iwasaki.kenichi@nihon-u.ac.jp
1st name | Yojiro |
Middle name | |
Last name | Ogawa |
Nihon University School of Medicine
Division of Hygiene, Department of Social Medicine
173-8610
30-1, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo
03-3972-8111
ogawa.yojiro@nihon-u.ac.jp
Division of Hygiene, Department of Social Medicine, Nihon University School of Medicine
Japan Society for the Promotion of Science
Non profit foundation
The institutional review board of Nihon University School of Medicine
30-1, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo
03-3972-8111
med.kenjim@nihon-u.ac.jp
NO
2016 | Year | 05 | Month | 09 | Day |
Published
15
Completed
2015 | Year | 06 | Month | 29 | Day |
2016 | Year | 06 | Month | 20 | Day |
2016 | Year | 06 | Month | 21 | Day |
2019 | Year | 03 | Month | 31 | Day |
2016 | Year | 05 | Month | 09 | Day |
2020 | Year | 02 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025633
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