Unique ID issued by UMIN | UMIN000022343 |
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Receipt number | R000025755 |
Scientific Title | Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulation |
Date of disclosure of the study information | 2016/05/19 |
Last modified on | 2018/12/27 01:13:53 |
Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulation
Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulation
Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulation
Optimization of intravenous vancomycin treatment schedule for pediatric population with Monte Carlo Simulation
Japan |
Patients under 18 years old who were administered intravenous vancomycin in Department of Pediatrics or Department of Pediatric Cardiology in our institute between April 1st 2011 and March 31st 2016.
Pediatrics |
Others
NO
To determine the optimal treatment schedule of vancomycin for pediatric patients with Monte Carlo Simulation.
Efficacy
The proportion of the patients who achieved more than 400 of AUC/MIC in the present treatment strategy in our institute.
To compare the duration required for body temperature to be normalized between the populations with AUC/MIC above 400 and below 400.
With Monte Carlo simulation, we will optimize the treatment strategy of vancomycin so that more than 90% of the patients achieve AUC/MIC more than 400.
Observational
Not applicable |
18 | years-old | > |
Male and Female
Patients who were administered intravenous vancomycin in Department of Pediatrics or Department of Pediatric Cardiology between April 1st 2011 and March 31st 2016.
Age under 18 years when vancomycin was initiated.
Written informed consent is obtained.
Patients with renal dysfunction.
Data unavailability exists.
Lack of informed consent.
100
1st name | |
Middle name | |
Last name | Reo Tanoshima |
Yokohama City University
Department of Pediatrics
Fukuura 3-9, Kanazawa-ku, Yokohama, Kanagawa, Japan
(+81)45-787-2800
tanotch@yokohama-cu.ac.jp
1st name | |
Middle name | |
Last name | Reo Tanoshima |
Yokohama City University
Department of Pediatrics
Fukuura 3-9, Kanazawa-ku, Yokohama, Kanagawa, Japan
(+81)45-787-2800
tanotch@yokohama-cu.ac.jp
Department of Pediatrics,
Yokohama City University
Department of Pediatrics,
Yokohama City University
Self funding
NO
2016 | Year | 05 | Month | 19 | Day |
Unpublished
No longer recruiting
2016 | Year | 05 | Month | 12 | Day |
2016 | Year | 05 | Month | 12 | Day |
Pediatric patients who were administered vancomycin between April 1st 2011 to March 31st 2016 in Department of Pediatrics or Department of Pediatric Cardiology.
2016 | Year | 05 | Month | 18 | Day |
2018 | Year | 12 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025755
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