Unique ID issued by UMIN | UMIN000022408 |
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Receipt number | R000025829 |
Scientific Title | Pregabalin versus acetaminophen for a treatment of chronic neuropathic pain on extremities after cervical surgery: A prospective randomized, open-label preliminary study |
Date of disclosure of the study information | 2016/05/25 |
Last modified on | 2016/05/23 13:25:46 |
Pregabalin versus acetaminophen for a treatment of chronic neuropathic pain on extremities after cervical surgery: A prospective randomized, open-label preliminary study
A prospective randomized study for chronic neuropathic pain after cervical surgery
Pregabalin versus acetaminophen for a treatment of chronic neuropathic pain on extremities after cervical surgery: A prospective randomized, open-label preliminary study
A prospective randomized study for chronic neuropathic pain after cervical surgery
Japan |
CSM OPLL
Orthopedics |
Others
NO
The objective of this study was to evaluate the safety and analgesic effect of pregabalin compared with ac-etaminophen for residual neuropathic pain in patients who received a cervical operation and to investigate which functional domains improve after treatment.
Safety,Efficacy
JOA score, JOACMEQ, NDI, VAS for pain
These items will be evaluated until 8 weeks after treatment.
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
oral administration of pregabalin
oral administration of acetaminophen
20 | years-old | <= |
75 | years-old | >= |
Male and Female
1:surgery for cervical degeneration such as spondylosis, herniation, or ossification of the posterior longitudinal ligament; 2:diagnosis of neuropathic pain and/or numbness of the upper and/or lower extremities lasting for at least 3 months after the operation; 3: Neuropathic Pain Screening Question-naire (painDETECT) score greater than or equal to 6 and visual analog scale (VAS) of neuropathic pain of the upper and/or lower extremities greater than 40mm;
1: diagnosis of cancer pain; 2: history of neuronal blockage using a neuro-destructive agent within 6 months; 3: pain on the upper and/or lower extremities that are caused by a reason other than a spinal disorder; 4: significant motor deficits and/or bowel or bladder dysfunction; and 5: history of another spinal operation.
60
1st name | |
Middle name | |
Last name | Takashi Hirai |
Tokyo Medical and Dental University
Department of Orthopedic Surgery
1-5-45 Yushima, Bunkyo-ku, Tokyo
03-5803-5279
hirai.orth@tmd.ac.jp
1st name | |
Middle name | |
Last name | Takashi Hirai |
Tokyo Medical and Dental University
Department of Orthopedic Surgery
1-5-45 Yushima, Bunkyo-ku, Tokyo
03-5803-5279
hirai.orth@tmd.ac.jp
Department of Orthopedic Surgery, Tokyo Medical and Dental University
Department of Orthopedic Surgery, Tokyo Medical and Dental University
Other
NO
2016 | Year | 05 | Month | 25 | Day |
Partially published
Completed
2011 | Year | 08 | Month | 01 | Day |
2011 | Year | 09 | Month | 01 | Day |
2016 | Year | 05 | Month | 23 | Day |
2016 | Year | 05 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000025829
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