Unique ID issued by UMIN | UMIN000022653 |
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Receipt number | R000026002 |
Scientific Title | Clinical evaluation of the noninvasive retinal and choroidal angiographic visualization using high resolution optical coherence tomography |
Date of disclosure of the study information | 2016/06/08 |
Last modified on | 2020/06/13 12:39:54 |
Clinical evaluation of the noninvasive retinal and choroidal angiographic visualization using high resolution optical coherence tomography
Clinical evaluation of high resolution OCT angiography
Clinical evaluation of the noninvasive retinal and choroidal angiographic visualization using high resolution optical coherence tomography
Clinical evaluation of high resolution OCT angiography
Japan |
Ocular fundus disease
Ophthalmology |
Others
NO
To evaluate the performance of chorioretinal blood vessel visualization and its characteristics themselves that could not be identified by conventional OCT for the clinical application after acquiring the images of the healthy eyes and the eyes with fundus abnormalities using high resolution OCT with 3micron depth resolution using OCT angiography techniques.
Others
To compare the chorioretinal blood vessel images using OCT angiography with the images using conventional fluorescein and indocyanine green angiography.
To evaluate the utility of 3 dimensional analysis from the obtained data.
To compare the chorioretinal blood vessel images of OCT angiography about the clarity and particularity between the target OCT device and other OCT devices by several examiners for clinical utility evaluation.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients with the ocular fundus disease and haelthy volunteers who consent to participate in this study
1. Subjects who a doctor declares difficulty of image acquisition because of cataract in slit lamp examination
2. Subjects who a doctor declares ineligible for any other reasons
100
1st name | Tomohiro |
Middle name | |
Last name | Iida |
Tokyo Women's Medical University School of Medicine
Ophthalmology
1628666
8-1 Kawadacho, Shinjuku-ku, Tokyo, JAPAN
03-3353-8111
iida@oph.twmu.ac.jp
1st name | Ichiro |
Middle name | |
Last name | Maruko |
Tokyo Women's Medical University School of Medicine
Ophthalmology
1628666
8-1 Kawadacho, Shinjuku-ku, Tokyo, JAPAN
03-3353-8111
imaruko@twmu.ac.jp
Tokyo Women's Medical University School of Medicine
Tokyo Women's Medical University School of Medicine
Other
CANON INC
Tokyo Women's Medical University School of Medicine
8-1 Kawadacho, Shinjuku-ku, Tokyo, JAPAN
03-3353-8111
krinri.bm@twmu.ac.jp
NO
2016 | Year | 06 | Month | 08 | Day |
https://link.springer.com/article/10.1007/s00417-019-04275-5
Unpublished
https://link.springer.com/article/10.1007/s00417-019-04275-5
27
The average PSNR for the A-images was 14.0 which was significantly higher than the 12.2 for the S-images (P<0.01). However, the average VD was 33.6% for the S-images and 34.8% for the A-images (P>0.1). The average FD was 1.67 for the S-images and 1.54 for the A-images (P<0.01). The mean luminance difference obtained by subtracting the luminance of the A-image from the S-image after BPF processing was 10.41 db which was positive for all eyes.
2020 | Year | 06 | Month | 13 | Day |
Twenty-seven eyes of 25 patients (18 men, 7 women; average age 71.0 years) with a CNV were examined by OCTA (OCT HS-100, Canon. Japan).
Analyses were performed on a single image (S-image) and the average of five single images of the same area (A-images).
None
the peak signal-to-noise ratio (PSNR), the vascular density (VD), fractal dimension (FD), and the noise component using band pass filter (BPF) processing of the S- and A-images of each case were compared.
No longer recruiting
2016 | Year | 05 | Month | 31 | Day |
2016 | Year | 05 | Month | 31 | Day |
2016 | Year | 07 | Month | 01 | Day |
2017 | Year | 12 | Month | 31 | Day |
2017 | Year | 12 | Month | 31 | Day |
2017 | Year | 12 | Month | 31 | Day |
Prospective observational study
Patients with the ocular fundus disease and haelthy volunteers who consent to participate. (Patients who visit or hospitalize to Tokyo Women's Medical University. Healthy volunteers who work at Tokyo Women's Medical University as a doctor.)
2016 | Year | 06 | Month | 08 | Day |
2020 | Year | 06 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026002
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