Unique ID issued by UMIN | UMIN000025553 |
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Receipt number | R000026046 |
Scientific Title | Effect of dose timing of antihypertensive drug on blood pressure variability and target organ damage |
Date of disclosure of the study information | 2017/01/11 |
Last modified on | 2019/03/28 18:17:26 |
Effect of dose timing of antihypertensive drug on blood pressure variability
and target organ damage
TIMING study
Effect of dose timing of antihypertensive drug on blood pressure variability
and target organ damage
TIMING study
Japan |
Hypertension
Cardiology |
Others
NO
We investigate how dose timing(morning or evening) of antihypertensive drug effect blood pressure variability
and target organ damage (CAVI: Cardio Ankle Vascular Index) in adult hypertensive patients.
Safety,Efficacy
Exploratory
CAVI( Cardio Ankle Vascular Index) in 6 mounts after randamization
Variability of blood pressure
Cardiovascular event
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Treatment
Medicine |
After getting an informed consent, patients are randamized into two groups (morning or evening). Controle 1 is morning group. After 6 mounts intervention, we will follow up the outcome for 7 years.
After getting an informed consent, patients are randamized into two groups (morning or evening). Controle 2 is evening group. After 6 mounts intervention, we will follow up the outcome for 7 years.
30 | years-old | <= |
Not applicable |
Male and Female
1. Hepertensive patients having antihypertensive drugs and over 135/85mmHg on morning blood pressure
2. Over 30 years old male and female
1) Chronic kidney disease patients under hemodialysis
2) Other severe patients( ex: terminal cancer, active collagen disease)
3) alcohol abuser
4) drug abuser
5) disability of independent gait
6) patients who can not get informed consent from themselves
7) inappropriate patients judged by doctors
100
1st name | |
Middle name | |
Last name | Kazuomi Kario |
Jichi Medical School
Cardiology
3311-1 Yakushiji Shimotsuke-city Tochigi-prefecture Japan
0285-44-2111
kkario@jichi.ac.jp
1st name | |
Middle name | |
Last name | Kei Sato |
Mitsui Memorial Hospital
Cardiology
1 Kanda Izumicho,Chiyoda-ku,Tokyo 101-8643, Japan
03-3862-9111
m02045ks@jichi.ac.jp
Jichi Medical School
Jichi Medical School
Non profit foundation
NO
2017 | Year | 01 | Month | 11 | Day |
Unpublished
Terminated
2016 | Year | 12 | Month | 02 | Day |
2017 | Year | 01 | Month | 10 | Day |
2017 | Year | 01 | Month | 11 | Day |
2025 | Year | 08 | Month | 31 | Day |
2017 | Year | 01 | Month | 05 | Day |
2019 | Year | 03 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026046
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