Unique ID issued by UMIN | UMIN000022598 |
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Receipt number | R000026047 |
Scientific Title | Study on inhibitory effect of teriparatide in knee osteoarthritis |
Date of disclosure of the study information | 2016/08/01 |
Last modified on | 2016/06/03 19:59:50 |
Study on inhibitory effect of teriparatide in knee osteoarthritis
Inhibitory effect of teriparatide in knee osteoarthritis
Study on inhibitory effect of teriparatide in knee osteoarthritis
Inhibitory effect of teriparatide in knee osteoarthritis
Japan |
Knee osteoarthritis
Orthopedics |
Others
NO
The purpose of this study is to clarify the inhibitory effect of teriparatide in progression of knee osteoarthrits
Efficacy
Exploratory
Change of joint space narrowing and bone trabecular integrity using plain X ray of knee joint at 2 years
MRI of knee joint, kL grade using plain X ray of knee joint, WOMAC score,and Knee society score at 2 years
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
Active
NO
YES
Institution is not considered as adjustment factor.
NO
Central registration
2
Treatment
Medicine |
teriparatide
VitaminD
60 | years-old | <= |
Not applicable |
Female
Primary ssteoprosis
Knee osteoarthritis with Kellgren-Lawrence grade 2 or 3
Patients with knee joint pain
History without treatment of osteoprosis, including hormone therapy, SERM,Bisphosfonate, teriparatide, anti RANKL antibody, eldecarcitol
Usage of glucocorticoide
Severe of knee osteoarthritis and deformity
Lower pain caused by lumber spine
History of knee joint surgery
Patient to lack in ability to know informed consent
Dementia
Contraindication to use teriparatide
Inadequate patient judged by doctors
60
1st name | |
Middle name | |
Last name | Shuichi Matsuda |
Kyoto University Hospital
Orthopedic surgery
54 Kawaharacho Shogoin Sakyo Kyoto Japan
0757513366
seikei@kuhp.kyoto-u.ac.jp
1st name | |
Middle name | |
Last name | Moritoshi Furu |
Kyoto University Hospital
Center for Rheumatic diseases
54 Kawaharacho Shogoin Sakyo Kyoto Japan
0757513877
morifuru@kuhp.kyoto-u.ac.jp
Department of Orthopedic Surgery, Kyoto Univeristy Graduate School of Medicine
Asahi Kasei Pharma
Profit organization
NO
2016 | Year | 08 | Month | 01 | Day |
Unpublished
Preinitiation
2016 | Year | 06 | Month | 03 | Day |
2016 | Year | 08 | Month | 01 | Day |
2016 | Year | 06 | Month | 03 | Day |
2016 | Year | 06 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026047
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