Unique ID issued by UMIN | UMIN000022775 |
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Receipt number | R000026246 |
Scientific Title | Effect of coadministration of ume paste (Prunus mume) and ginger powder on serum uric acid level |
Date of disclosure of the study information | 2016/06/20 |
Last modified on | 2018/12/20 14:54:19 |
Effect of coadministration of ume paste (Prunus mume) and ginger powder on serum uric acid level
Effect of coadministration of ume paste (Prunus mume) and ginger powder on serum uric acid level
Effect of coadministration of ume paste (Prunus mume) and ginger powder on serum uric acid level
Effect of coadministration of ume paste (Prunus mume) and ginger powder on serum uric acid level
Japan |
Healthy volunteers, mild hyperuricemia
Medicine in general | Adult |
Others
NO
To determine the effect of coadministration of ume paste and ginger powder on serum uric acid level.
Efficacy
Confirmatory
Explanatory
Not applicable
Serum uric acid level at baseline, 4, 8, and 12 weeks.
Uric acid clearance and urinary pH at baseline, 4, 8, and 12 weeks.
Platelet aggregation test, thromboxane B2, and MDA (malondialdehyde) levels at baseline and 12 weeks.
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
YES
NO
YES
Central registration
2
Prevention
Food |
Subjects receive 4 capsules (1200 mg)/day containing ume paste and ginger powder for 12 weeks.
Subjects receive 4 placebo capsules (1200 mg)/day for 12 weeks.
20 | years-old | <= |
70 | years-old | >= |
Male
Serum uric acid 6.0-7.9 mg/dL
1) Taking anti-hyperuricemic drugs
2) History of gouty arthritis, gouty node, and/or gouty attack
3) Taking medicines or receiving health guidance for hypertension, diabetes, hyperlipidemia, and/or metabolic syndrome
4) Taking drugs or functional food that may affect serum uric acid level
5) Participation in any clinical trial within 90 days of the commencement of the trial
6) CKD stage >=A2 and/or >=G3a
7) History of severe disease and/or major surgery
8) Judged as ineligible by clinical investigators.
50
1st name | |
Middle name | |
Last name | Fumiko Higashikawa |
Hiroshima University, Institute of Biomedical & Health Sciences
Project Research Center for Clinical Trial and Preventive Medicine
Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, JAPAN
082-257-1533
fumiko@hiroshima-u.ac.jp
1st name | |
Middle name | |
Last name | Fumiko Higashikawa |
Hiroshima University, Institute of Biomedical & Health Sciences
Project Research Center for Clinical Trial and Preventive Medicine
Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, JAPAN
082-257-1533
fumiko@hiroshima-u.ac.jp
Hiroshima University
KAWAMOTO FOODS CO., LTD.
Profit organization
NO
2016 | Year | 06 | Month | 20 | Day |
Unpublished
Completed
2016 | Year | 06 | Month | 15 | Day |
2016 | Year | 08 | Month | 01 | Day |
2016 | Year | 06 | Month | 17 | Day |
2018 | Year | 12 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026246
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