Unique ID issued by UMIN | UMIN000022984 |
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Receipt number | R000026423 |
Scientific Title | A cohort study of anthracycline-induced cardiotoxicity |
Date of disclosure of the study information | 2016/08/01 |
Last modified on | 2022/01/04 16:34:00 |
A cohort study of anthracycline-induced cardiotoxicity
A cohort study of anthracycline-induced cardiotoxicity
A cohort study of anthracycline-induced cardiotoxicity
A cohort study of anthracycline-induced cardiotoxicity
Japan |
All patients scheduled for anthracycline-containing therapy for various kinds of tumors
Cardiology | Hematology and clinical oncology | Breast surgery |
Obstetrics and Gynecology |
Malignancy
NO
To evaluate the incidence of anthracycline-induced cardiotoxicity and find predictive factors markers in cancer patients
Safety
Exploratory
Pragmatic
Not applicable
The incidence of cardiotoxicity defined as a reduction in left ventricular ejection fraction (LVEF) >10 percentage points from baseline and <50%
All cause death, the following cardiac events (cardiac death, acute pulmonary edema, acute coronary syndromes, llife-threatening arrhythmias), the recovery from cadiotoxicity after the initiation of heart failure treatment defined as EF>50%
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Device,equipment |
Echocardiac examination (before & during anthracycline treatment, after 3, 6, 9, 12, 18, 24 month)
20 | years-old | <= |
Not applicable |
Male and Female
1) malignancy patients in the face of with anthracycline chemotherapy
2) age more than 20 years old
3) EF > 50%
4) life expectancy of > 1year
5) written informed consent
1) cases with valuvular heart disease, gongenital heart disease, and cardiomyopathy
2) pregnant or lactating women
3) psychotic disorder
500
1st name | Kazuko |
Middle name | |
Last name | Tajiri |
University of Tsukuba Hospital
Cardiovascular Division
305-8576
Amakubo 2-1-1, Tsukuba, Ibaraki
029-853-3143
ktajiri@md.tsukuba.ac.jp
1st name | Kazuko |
Middle name | |
Last name | Tajiri |
University of Tsukuba Hospital
Cardiovascular Division
305-8576
Amakubo 2-1-1, Tsukuba, Ibaraki
029-853-3143
ktajiri@md.tsukuba.ac.jp
University of Tsukuba
University of Tsukuba
Self funding
University of Tsukuba Hospital
2-1-1 Amakubo, Tsukuba
029-853-3914
rinshokenkyu@un.tsukuba.ac.jp
NO
筑波大学附属病院(茨城県)、水戸協同病院(茨城県)
2016 | Year | 08 | Month | 01 | Day |
Unpublished
500
No longer recruiting
2016 | Year | 06 | Month | 30 | Day |
2016 | Year | 07 | Month | 13 | Day |
2016 | Year | 08 | Month | 01 | Day |
2023 | Year | 12 | Month | 31 | Day |
2016 | Year | 07 | Month | 02 | Day |
2022 | Year | 01 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026423
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