UMIN-CTR Clinical Trial

BACK TOP
UMIN-CTR English Home Glossary (Simple) FAQ Search clinical trials

Name:
UMIN ID:

Recruitment status Terminated
Unique ID issued by UMIN UMIN000022950
Receipt No. R000026454
Scientific Title Is the intravenous dexamethasone non-inferior to the perineural dexamethasone regarding the effect of prolonging duration of local anesthesia? Systematic review and a Bayesian network meta-analysis of randomized trials.
Date of disclosure of the study information 2016/10/01
Last modified on 2018/07/02

* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments


Basic information
Public title Is the intravenous dexamethasone non-inferior to the perineural dexamethasone regarding the effect of prolonging duration of local anesthesia? Systematic review and a Bayesian network meta-analysis of randomized trials.
Acronym Is the intravenous dexamethasone non-inferior to the perineural dexamethasone regarding the effect of prolonging duration of local anesthesia? Systematic review and a Bayesian network meta-analysis of randomized trials.
Scientific Title Is the intravenous dexamethasone non-inferior to the perineural dexamethasone regarding the effect of prolonging duration of local anesthesia? Systematic review and a Bayesian network meta-analysis of randomized trials.
Scientific Title:Acronym Is the intravenous dexamethasone non-inferior to the perineural dexamethasone regarding the effect of prolonging duration of local anesthesia? Systematic review and a Bayesian network meta-analysis of randomized trials.
Region
Japan

Condition
Condition surgeries required peripheral nerve block
Classification by specialty
Anesthesiology
Classification by malignancy Others
Genomic information NO

Objectives
Narrative objectives1 To compare the effect of prolonging duration of local anesthesia between intravenous and perineural dexamethasone under non-inferiority hypothesis.
Basic objectives2 Safety,Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase

Assessment
Primary outcomes the duration of analgesia or sensory block
Key secondary outcomes the duration of motor blockade
the failure rate of the nerve block,
the incidence of PONV
pain scores
any complication

Base
Study type Others,meta-analysis etc

Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

Eligibility
Age-lower limit

Not applicable
Age-upper limit

Not applicable
Gender Male and Female
Key inclusion criteria Randomized controlled trials including the following PICO:
Patients) receiving any peripheral nerve block
Intervention and Control) intravenous and/or perineural dexamethasone and placebo
Outcome) the duration of analgesia.
Key exclusion criteria case reports, reviews, manikin studies, and animal studies. Eligibility is not restricted by language.
Target sample size 0

Research contact person
Name of lead principal investigator
1st name
Middle name
Last name Takahiro Mihara
Organization Kanagawa Children's Medical Center
Division name Department of Anesthesiology
Zip code
Address 2-138-4 Mutsukawa, Minami-ku, Yokohama 232-8555, Japan
TEL 045-711-2351
Email miharaxxxtotoro@yahoo.co.jp

Public contact
Name of contact person
1st name
Middle name
Last name Takahiro Mihara
Organization Kanagawa Children's Medical Center
Division name Department of Anesthesiology
Zip code
Address 2-138-4 Mutsukawa, Minami-ku, Yokohama 232-8555, Japan
TEL 045-711-2351
Homepage URL
Email miharaxxxtotoro@yahoo.co.jp

Sponsor
Institute Kanagawa Children's Medical Center
Institute
Department

Funding Source
Organization Kanagawa Children's Medical Center
Organization
Division
Category of Funding Organization Local Government
Nationality of Funding Organization

Other related organizations
Co-sponsor
Name of secondary funder(s)

IRB Contact (For public release)
Organization
Address
Tel
Email

Secondary IDs
Secondary IDs NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions

Other administrative information
Date of disclosure of the study information
2016 Year 10 Month 01 Day

Related information
URL releasing protocol
Publication of results Unpublished

Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description

Progress
Recruitment status Terminated
Date of protocol fixation
2016 Year 06 Month 30 Day
Date of IRB
Anticipated trial start date
2016 Year 07 Month 01 Day
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Other
Other related information the details of the study protocol are presented in the attached files.

Management information
Registered date
2016 Year 06 Month 30 Day
Last modified on
2018 Year 07 Month 02 Day


Link to view the page
URL(English) https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026454

Research Plan
Registered date File name
2016/06/30 Study Protocol.ver01.docx

Research case data specifications
Registered date File name

Research case data
Registered date File name


Contact us.