Unique ID issued by UMIN | UMIN000023366 |
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Receipt number | R000026922 |
Scientific Title | A study on effects of anti- hepatitis C virus treatment on reactivation of hepatitis B virus. |
Date of disclosure of the study information | 2016/07/28 |
Last modified on | 2023/08/18 11:11:49 |
A study on effects of anti- hepatitis C virus treatment on reactivation of hepatitis B virus.
Effect of anti-HCV treatment on HBV reactivation
A study on effects of anti- hepatitis C virus treatment on reactivation of hepatitis B virus.
Effect of anti-HCV treatment on HBV reactivation
Japan |
Patients with chronic HCV infection
Hepato-biliary-pancreatic medicine |
Others
NO
To evaluate the frequency of HBV reactivation during and after anti-HCV therapy and to investigate the predictors obtained at baseline and affecting the HBV reactivation
Safety
To investigate the frequency of the HBV reactivation
1.To analyze the predictors for HBV reactivation during and after anti-HCV therapy.
2.To analyze the change in HBs antibody titer during and after anti-HCV therapy and to analyze the predictors related to HBs antibody decline.
3.To conduct stratified analysis based on treatment with or without IFN
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients (1) with the target disease who (2) satisfy all the inclusion criteria and (3) meet none of the exclusion criteria are eligible for the study.
(1) Subjects
Patients treated with anti-HCV therapy between January 2001 and December 2018 and having proper preserved serum for research
(2) Inclusion criteria
[1] Patients who are 20 years of age or older at the time of treatment
[2] Patients who have been treated with anti-HCV therapy
[3] Patients with an informed consent or patients without rejection to entry this study
1) Patients with poorly controlled cardiac disease (e.g., myocardial infarction, cardiac failure, arrhythmia)
2) Patients with severe hepatic impairment
3) Patients deemed unsuitable for study entry by their treating physician or principal investigator
400
1st name | goki |
Middle name | |
Last name | Suda |
Hokkaido University
Department of Gastroenterology and Hepatology, Graduate School of Medicine
060-8638
Kita 14-jo Nishi 5-jo, Kita-ku, Sapporo city, Hokkaid
011-716-1161
gsudgast@pop.med.hokudai.ac.jp
1st name | GOki |
Middle name | |
Last name | Suda |
Hokkaido University
Department of Gastroenterology and Hepatology, Graduate School of Medicine,
060-8648
Kita 14-jo Nishi 5-jo, Kita-ku, Sapporo city, Hokkaid
011-716-1161
gsudgast@pop.med.hokudai.ac.jp
Hokkaido University Department of Gastroenterology and Hepatology, Graduate School of Medicine,
none
Self funding
Hokkaido University Hospital Division of Clinical Research Administration
North 14, West 4, Kita-ku
011-706-7636
crjimu@huhp.hokudai.ac.jp
NO
2016 | Year | 07 | Month | 28 | Day |
Unpublished
Completed
2016 | Year | 03 | Month | 28 | Day |
2016 | Year | 04 | Month | 28 | Day |
2016 | Year | 07 | Month | 28 | Day |
2022 | Year | 12 | Month | 31 | Day |
To investigate the frequency of the HBV reactivation
1 To analyze the predictors for HBV reactivation during and after anti-HCV therapy.
2 To analyze the change in HBs antibody titer during and after anti-HCV therapy and to analyze the predictors related to HBs antibody decline.
3 To conduct stratified analysis based on treatment with or without IFN
2016 | Year | 07 | Month | 27 | Day |
2023 | Year | 08 | Month | 18 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026922
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