Unique ID issued by UMIN | UMIN000023428 |
---|---|
Receipt number | R000026976 |
Scientific Title | The association between monocyte subsets and coronary plaque characteristics-a retrospective study- |
Date of disclosure of the study information | 2016/08/20 |
Last modified on | 2020/12/13 09:37:16 |
The association between monocyte subsets and coronary plaque characteristics-a retrospective study-
The association between monocyte and coronary plaque characteristics in patients with angina pectoris
The association between monocyte subsets and coronary plaque characteristics-a retrospective study-
The association between monocyte and coronary plaque characteristics in patients with angina pectoris
Japan |
Angina pectoris with impaired glucose torerance or diabetes mellitus and patients who are suspected that disease
Cardiology | Endocrinology and Metabolism |
Others
NO
This study aims to investigate the effect of monocyte subsets on coronary plaque properties, and to investigate the association of glucose fluctuation,inflammatory cells, immune cells assessd by flowcytometry and plaque properties.
Others
Pathophysiology
Not applicable
1.Coronary plaque characteristics using the optical coherence tomography (OCT) and intravascular ultrasound(IVUS) and coronary angiography
2.Association between atherosclerosis assessed by IVUS or OCT and subsets of monocyte.
3.Circadian rhythm in the blood glucose using CGM
1.Glucose, IRI, CPR assesed by glucose tolerance test.
2.Intima- media thickness(IMT) assesed by carotid artery ultrasound.
3.Endothelial function assessed by FMD.
4.Inflammatory cell marker associated with arteriosclerosis.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Retrospective observational study.
Patinets who was undergone coronary angiography and monocytes subsets using flow cytometry after April 2015 in Kobe university
1)Patients with renal dysfunction(Creatinin level is more than 2.0mg/ml) or reciving hemodaialysis.
2)the patients who have had heart failure (NYHA >III)
3)patients with any malignant tumor or very ill condition
4)pregnant women or women at risk of becoming pregnant
65
1st name | |
Middle name | |
Last name | Shinke Toshirou |
Kobe univercity hospital
Cardiovascular medicine
7-5-2 Kusunoki-cho, Chuo-ku, Kobe City,650-0017
078-382-5111
shinke@med.kobe-u.ac.jp
1st name | |
Middle name | |
Last name | Yamamoto Hiroyuki |
Kobe university hospital
Cardiovascular medicine
7-5-2 Kusunoki-cho, Chuo-ku, Kobe City,650-0017
078-382-5111
y0493589m@hotmail.co.jp
Kobe University Hospital department of cardiovascular medicne
Kobe univetsity
Self funding
NO
2016 | Year | 08 | Month | 20 | Day |
Unpublished
Completed
2015 | Year | 04 | Month | 01 | Day |
2016 | Year | 08 | Month | 08 | Day |
2015 | Year | 04 | Month | 01 | Day |
2018 | Year | 03 | Month | 31 | Day |
2018 | Year | 03 | Month | 31 | Day |
retrospecive observational study
2016 | Year | 08 | Month | 01 | Day |
2020 | Year | 12 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000026976
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |