Unique ID issued by UMIN | UMIN000024259 |
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Receipt number | R000027929 |
Scientific Title | Does oral care prevent post-ESD-pneumonia? |
Date of disclosure of the study information | 2016/10/10 |
Last modified on | 2021/09/13 10:17:30 |
Does oral care prevent post-ESD-pneumonia?
ESD oral care study
Does oral care prevent post-ESD-pneumonia?
ESD oral care study
Japan |
early gastric cancer/gastric adenoma
Gastroenterology |
Malignancy
NO
We consider whether oral care is useful for post-ESD-pneumonia.
Efficacy
Post-ESD-pneumonia rate
Post-ESD-fever, inflammatory reaction, hospitalization period and fee
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
2
Prevention
Maneuver |
Oral care is performed.
Oral care is not performed.
20 | years-old | <= |
Not applicable |
Male and Female
1) Clinical diagnosis of Stage IA early gastric cancer or gastric adenoma, and suspicion for Stage IA early gastric cancer or gastric adenoma.
2) 20 years old or older.
3) Obtain patients consent
Unsuitable patient
302
1st name | Yuko |
Middle name | |
Last name | Akazawa |
Nagasaki University Hospital
Department of Pathology
852-8501
1-7-1 Sakamoto, Nagasaki, Japan
095-819-7562
akazaway@nagasaki-u.ac.jp
1st name | Taro |
Middle name | |
Last name | Akashi |
Nagasaki University Hospital
Department of Gastroenterology and Hepatology
852-8501
1-7-1 Sakamoto, Nagasaki, Japan
095-819-7481
fuk_naga_ta23@yahoo.co.jp
Nagasaki University Hospital
Nagasaki University Hospital
Other
Nagasaki University Hospital administration office
1-7-1 Sakamoto, Nagasaki, Japan
095-819-7217
mh-shomu@ml.nagasaki-u.ac.jp
NO
長崎大学病院(長崎県)
JCHO諫早総合病院(長崎県)
2016 | Year | 10 | Month | 10 | Day |
https://pubmed.ncbi.nlm.nih.gov/33106696/
Published
https://pubmed.ncbi.nlm.nih.gov/33106696/
60
Sixty-one patients who underwent ESD for gastric neoplasms were randomly assigned to the oral care or control groups. Of 60 patients whose data were available for analysis, 5 (8.3%) experienced pneumonia . The post-oral care bacteria count was significantly higher in the saliva of patients who developed pneumonia compared to those without pneumonia. In addition, the presence of vascular brain diseases and the dose of meperidine were also significantly associated with the occurrence of pneumonia.
2021 | Year | 03 | Month | 12 | Day |
Patients who underwent endoscopic submucosal dissection (ESD) for gastric neoplasm.
After the informed consent, patients were randomized to oral care group and non-oral care group.
N/A
Bacterial counts before and after oral care.
Occurrence of pneumonia after ESD
CRP before and after ESD
Use of narcotic drugs during ESD
Completed
2016 | Year | 07 | Month | 25 | Day |
2016 | Year | 10 | Month | 20 | Day |
2016 | Year | 12 | Month | 19 | Day |
2018 | Year | 03 | Month | 11 | Day |
2018 | Year | 03 | Month | 13 | Day |
2018 | Year | 03 | Month | 20 | Day |
2018 | Year | 03 | Month | 30 | Day |
2016 | Year | 10 | Month | 02 | Day |
2021 | Year | 09 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027929
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