Unique ID issued by UMIN | UMIN000024275 |
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Receipt number | R000027949 |
Scientific Title | Therapeutic efficacy of magnesium oxide for peripheral artery disease among patients undergoing hemodialysis - Open label randomized controlled trial |
Date of disclosure of the study information | 2016/12/15 |
Last modified on | 2019/10/06 09:15:29 |
Therapeutic efficacy of magnesium oxide for peripheral artery disease among patients undergoing hemodialysis - Open label randomized controlled trial
Therapeutic efficacy of magnesium oxide for peripheral artery disease
Therapeutic efficacy of magnesium oxide for peripheral artery disease among patients undergoing hemodialysis - Open label randomized controlled trial
Therapeutic efficacy of magnesium oxide for peripheral artery disease
Japan |
Peripheral artery disease
Cardiology | Nephrology |
Others
NO
To evaluate therapeutic efficacy of magnesium oxide on peripheral artery disease of patients undergoing hemodialysis.
Efficacy
Exploratory
Not applicable
skin perfusion pressure
ankle brachial index
capillary analysis system
bone turnover markers (bone alkaline phosphatase, TRACP-5b, parathyroid hormone)
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
No treatment
YES
Central registration
2
Treatment
Medicine |
Intervention group: Magnesium oxide
Administration period: 12 months
Target range of serum magnesium levels: 2.7-3.3 mg/dL
no treatment
20 | years-old | <= |
Not applicable |
Male and Female
1. Patients undergoing maintenance hemodialysis/hemodiafiltration and aged 20 years or older.
2. Patients with SPP of less than 80 mmHg.
3. Patients with gastroduodenal ulcer and/or gastritis and/or dyspepsia.
1. Patients with serum magnesium levels of 3.4 mg/dL or greater.
2. Patients who had experienced side effects by magnesium oxide or rebamipide.
3. Patients currently taking magnesium oxide.
4. Patients suffering from critical limb ischemia.
5. Patients currently taking part in other interventional studies.
90
1st name | |
Middle name | |
Last name | Takayuki Hamano |
Osaka University Graduate School of Medicine
Department of Comprehensive Kidney Disease Research
2-2, Yamada-oka, Suita, Japan
0668793857
hamatea@kid.med.osaka-u.ac.jp
1st name | |
Middle name | |
Last name | Yusuke Sakaguchi |
Osaka University Graduate School of Medicine
Department of Comprehensive Kidney Disease Research
2-2, Yamada-oka, Suita, Japan
0668793857
yusuke7771@gmail.com
Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine
Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine
Other
NO
医療法人 徳靖会 小尾クリニック
医療法人 和光会 橋中診療所
2016 | Year | 12 | Month | 15 | Day |
Unpublished
Completed
2017 | Year | 01 | Month | 11 | Day |
2017 | Year | 01 | Month | 11 | Day |
2017 | Year | 01 | Month | 11 | Day |
2019 | Year | 10 | Month | 06 | Day |
2016 | Year | 10 | Month | 03 | Day |
2019 | Year | 10 | Month | 06 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027949
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