Unique ID issued by UMIN | UMIN000024562 |
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Receipt number | R000028261 |
Scientific Title | Evaluation of suppressive effect of persimmon leaf powders on postpradial blood glucose levels. |
Date of disclosure of the study information | 2016/10/27 |
Last modified on | 2017/04/25 09:18:43 |
Evaluation of suppressive effect of persimmon leaf powders on postpradial blood glucose levels.
Evaluation of suppressive effect of persimmon leaf powders on postpradial blood glucose levels.
Evaluation of suppressive effect of persimmon leaf powders on postpradial blood glucose levels.
Evaluation of suppressive effect of persimmon leaf powders on postpradial blood glucose levels.
Japan |
Healthy volunteers
Adult |
Others
NO
Evaluation of the suppressive effect of coingestion of persimmon leaf powders with white rice on postpradial blood glucose levels in high glycemic responders to white rice of healthy subjects.
Efficacy
Time-dependent changes in postprandial blood glucose levels.
The incremental area under the blood glucose response curve (IAUC) and Glycemic index (GI) value.
Interventional
Cross-over
Randomized
Individual
Single blind -participants are blinded
Placebo
2
Prevention
Food |
Test meal: coingestion of persimmon leaf powders (3 g) in water (200 mL) with Koshihikari white rice (147 g) > Washout period: one week > Control meal: coingestion of water (200 mL) with Koshihikari white rice (147 g)
Control meal: coingestion of water (200 mL) with Koshihikari white rice (147 g) > Washout period: one week > Test meal: coingestion of persimmon leaf powders (3 g) in water (200 mL) with Koshihikari white rice (147 g)
20 | years-old | <= |
70 | years-old | > |
Male and Female
1.Volunteers of high IAUC responders to white rice (3500 min mg/dL <, for 120 min) in healthy subjects, by finger-prick blood measurement at 0 (preintake), 15, 30, 45, 60, 90 and 120 min postintake of white rice.
2.Volunteers being able to make self-judgent to particupate in this study and giving written informed consent.
3.Volunteers having screening test results judged to be appropriate for this study by investigator.
1.Volunteers having severe history of the diseases (liver, kidney, hert, blood) judged to be inappropriate for this study.
2.Volunteers received gastrectomy, enterectomy, or gastro-intestinal diseases, judged to be inappropriate for this study.
3.Diabetes mellitus.
4.Subjects who use oral medication affecting blood glucose.
5.Volunteers with any other medical reasons judged to be inappropriate by chief investigater.
15
1st name | |
Middle name | |
Last name | Kenichi Watanabe |
Niigata Universty of Pharmacy and Applied Life Sciences
Laboratory of Clinical pharmacology
265-1, Higashijima, Akiha-ku, Niigata City
0250-25-5267
watanabe@nupals.ac.jp
1st name | |
Middle name | |
Last name | Niigata Bio-Research Park, Inc |
Niigata Bio-Research Park, Inc
Business promotion division
316-2 Higashijima, Akiha-ku, Niigata, 956-0811, Japan
0250-25-1196
goto@nbrp.co.jp
Niigata Bio-Research Park, Inc
Niigata City Agricultural Development Research Center
Local Government
NO
2016 | Year | 10 | Month | 27 | Day |
Unpublished
Completed
2016 | Year | 10 | Month | 05 | Day |
2016 | Year | 10 | Month | 28 | Day |
2016 | Year | 10 | Month | 25 | Day |
2017 | Year | 04 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028261
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