Unique ID issued by UMIN | UMIN000024630 |
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Receipt number | R000028335 |
Scientific Title | Study of oral health control and probiotics in the elderly people |
Date of disclosure of the study information | 2016/11/03 |
Last modified on | 2019/02/26 09:17:44 |
Study of oral health control and probiotics in the elderly people
Oral health and probiotics
Study of oral health control and probiotics in the elderly people
Oral health and probiotics
Japan |
healthy elderly people
Dental medicine | Adult |
Others
YES
The aim is to assess the effect of lactic acid bacteria-containing tablets on oral health control.
Efficacy
Exploratory
Pragmatic
Not applicable
Change of oral health condition by the oral administration of lactic acid bacteria-containing tablets for 2 months: Plaque index, tongue coating, probing pocket depth, bleeding on probing, volatile sulfur compound.
composition of oral microbiota
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
The subjects ingest the tablets containing Lactobacillus salivarius WB21 for 2 months. The dose throughout the test period is maintained at 1 tablet 3 times per day (2.0 x 10^9 colony forming units per day), taken orally after eating and mouth cleaning.
The subjects ingest the placebo tablets for 2 months. The dose throughout the test period is maintained at 1 tablet 3 times per day, taken orally after eating and mouth cleaning. The placebo tablets are same composition except for L. salivarius WB21.
60 | years-old | <= |
Not applicable |
Male and Female
Healthy elderly people
not wearing complete denture prostheses, not currently visiting a dentist for treatment, not using antibiotics within 3 months, having no smoking habit, having no adverse reactions to lactose or fermented milk products, having no serious metabolic disorders, having no cancer
30
1st name | |
Middle name | |
Last name | Takao Hirofuji |
Fukuoka Dental College
Department of General Dentistry
2-15-1, Tamura Sawara-ku, Fukuoka, Japan
81-91-801-0411
hirofuji@college.fdcnet.ac.jp
1st name | |
Middle name | |
Last name | Nao Taniguchi |
Fukuoka Dental College
Department of Preventive and Public Health Dentistry
2-15-1, Tamura Sawara-ku, Fukuoka, Japan
81-91-801-0411
naojsz@college.fdcnet.ac.jp
Fukuoka Dental College
Ministry of Education, Culture, Sports, Science and Technology
Japanese Governmental office
NO
筑紫南コミュニティセンター(福岡県)
2016 | Year | 11 | Month | 03 | Day |
Partially published
Completed
2016 | Year | 08 | Month | 01 | Day |
2016 | Year | 08 | Month | 01 | Day |
2017 | Year | 06 | Month | 30 | Day |
2016 | Year | 10 | Month | 29 | Day |
2019 | Year | 02 | Month | 26 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028335
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