Unique ID issued by UMIN | UMIN000024737 |
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Receipt number | R000028360 |
Scientific Title | To elucidate the role of PBMC mitochondria in obese subjects |
Date of disclosure of the study information | 2016/11/10 |
Last modified on | 2022/03/26 17:33:03 |
To elucidate the role of PBMC mitochondria in obese subjects
BLOODMITO-OBESITY
To elucidate the role of PBMC mitochondria in obese subjects
BLOODMITO-OBESITY
Japan |
Obesity
Cardiology | Endocrinology and Metabolism |
Others
NO
To test the hypothesis that mitochondrial function in peripheral blood mononuclear cells (PBMC) may be impaired in obese subjects and lifestyle changes including diet and exercise may improve PBMC mitochondrial function in these patients
Efficacy
PBMC mitochondrial function
Systemic oxidative stress
Systemic imflammatory markers
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Prevention
Behavior,custom |
Instruction to improve lifestyle (e.g. diet and exercise) by health-care providers
18 | years-old | <= |
Not applicable |
Male and Female
Obese subjects with more than 30 in BMI diagnosed in regular physical check-up
1.Subjects with active chronic inflammatory disease
2.Subjects who receive steroid or immunosuppressant drugs
3.Subjects who cannot give written informed consent
4.Subjects who are considered to be inappropriate for the study by principal investigator
77
1st name | Takashi |
Middle name | |
Last name | Yokota |
Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Department of Cardiovascular Medicine
060-8638
Kita-15 Nishi-7, Kita-Ku, Sapporo, Japan
011-706-6973
t-yokota@med.hokudai.ac.jp
1st name | Takashi |
Middle name | |
Last name | Yokota |
Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Department of Cardiovascular Medicine
060-8638
Kita-15 Nishi-7, Kita-Ku, Sapporo, Japan
011-706-6973
t-yokota@med.hokudai.ac.jp
Hokkaido University
Ministry of Education, Culture, Sports, Science and Technology (Japan)
Japanese Governmental office
Institutional Review Board of Faculty of Medicine and Graduate School of Medicine in Hokkaido University
Kita-15 Nishi-7, Kita-Ku, Sapporo 060-8638, Japan
011-706-5003
shomu@med.hokudai.ac.jp
NO
2016 | Year | 11 | Month | 10 | Day |
Unpublished
No longer recruiting
2016 | Year | 09 | Month | 16 | Day |
2016 | Year | 09 | Month | 16 | Day |
2016 | Year | 11 | Month | 10 | Day |
2020 | Year | 07 | Month | 01 | Day |
1.Prospective study
2.A case-control study (Control group: healthy subjects with BMI<25) is also included only before intervention
2016 | Year | 11 | Month | 07 | Day |
2022 | Year | 03 | Month | 26 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028360
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