Unique ID issued by UMIN | UMIN000024783 |
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Receipt number | R000028512 |
Scientific Title | The Current of Frailty in Patients with Chronic Hemodialysis |
Date of disclosure of the study information | 2016/11/10 |
Last modified on | 2017/11/14 13:22:50 |
The Current of Frailty in Patients with Chronic Hemodialysis
Frailty in Hemodialysis Patients
The Current of Frailty in Patients with Chronic Hemodialysis
Frailty in Hemodialysis Patients
Japan |
Frailty
Geriatrics |
Others
NO
The ESRD population is also aging worldwide, particularly in Japan. Mean age of all Japanese prevalent ESRD populations is 67.2 years and 61.8 percent of patients were 65 years old and above, and 30.3 percent were 75 years old and above at the end of 2013. According to the Fried definition, the frailty status has been documented in 7 percent of elderly population, 14 percent of CKD patients without dialysis and 42 percent of hemodialysis (HD) adult ESRD patients. Japanese elderly populations and CKD patients at frailty status are almost comparable with above-mentioned prevalence. However, the status of frailty in Japanese HD patients remains unknown.
The purpose of this study is to identify the prevalence and predictors of frailty in Japanese HD patients.
Others
the comparison of frailty between elderly and non-elderly
Exploratory
Explanatory
Not applicable
the prevalence of frailty in patients with hemodialysis
the predictors of frailty
Observational
20 | years-old | <= |
Not applicable |
Male and Female
The subjects were all chronic HD patients who regularly visited the institutions within the period of this study, and who agreed with the aim and protocol of the present study.
The initial exclusion criteria were: refusal to participate, hospitalization due to accidents or sickness, and patients with difficulties to answer the questionnaire. Finally, we excluded participants who did not fill the frailty contents in questionnaire completely, from those remaining after initial exclusion.
500
1st name | |
Middle name | |
Last name | Haruhito A. Uchida |
Okayama University
Department of Nephrology, Rheumatology, Endocrinology and Metabolism
2-5-1 SHIKATA-CHO KITA-KU, Okayama 700-8558, Japan
086-235-7235
hauchida@okayama-u.ac.jp
1st name | |
Middle name | |
Last name | Haruhito A. Uchida |
Okayama University
Department of Nephrology, Rheumatology, Endocrinology and Metabolism
2-5-1 SHIKATA-CHO KITA-KU, Okayama 700-8558, Japan
086-235-7235
hauchida@okayama-u.ac.jp
Department of Medicine, Innnoshima General Hospital, Hiroshima, Japan
None
Other
Nippon Kokan Fukuyama Hospital, Sumitomo Besshi Hospital, Mihara Shiromachi Hospital, Akaiwa Ishikai Hospital and Sugimoto Clinic
NO
因島総合病院(広島県)、日本鋼管福山病院(広島県)、住友別子病院(愛媛県)、三原城町病院(広島県)、赤磐医師会病院(岡山県)、杉本クリニック(岡山県)
2016 | Year | 11 | Month | 10 | Day |
Published
Of the 542 patients visiting each institution, 388 were enrolled in this study. In total, 26.0 percent of participants were categorized as not-frailty, 52.6 percent as pre-frailty and 21.4 percent as frailty. The prevalence of frailty increased steadily with age and was more prevalent in females than in males and the subjects with frailty received polypharmacy. A multivariate logistic regression analysis revealed that the factors independently associated with frailty were the following: female gender (OR 3.661), age (OR 1.065), age above 75 years old (OR 4.892), body mass index (BMI) bellow 18.5 (OR 0.110), number of medications being taken (OR 1.351), diabetes mellitus (DM) (OR 2.765) and MNA-SF bellow 11 (OR 7.405). Frailty was associated with the accumulation of risk factors.
Completed
2015 | Year | 08 | Month | 17 | Day |
2015 | Year | 10 | Month | 01 | Day |
2016 | Year | 01 | Month | 31 | Day |
2017 | Year | 11 | Month | 13 | Day |
2017 | Year | 11 | Month | 13 | Day |
2017 | Year | 11 | Month | 13 | Day |
This result will be published on the "Aging and Disease" in Februaly 2018.
The detail is placed on bellow URL.
http://www.aginganddisease.org/EN/10.14336/AD.2017.0429
2016 | Year | 11 | Month | 10 | Day |
2017 | Year | 11 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028512
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