Unique ID issued by UMIN | UMIN000025000 |
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Receipt number | R000028762 |
Scientific Title | Effect of Bifidobacteria intake on oral environment |
Date of disclosure of the study information | 2017/01/15 |
Last modified on | 2018/03/30 19:42:18 |
Effect of Bifidobacteria intake on oral environment
Effect of Bifidobacteria intake on oral environment
Effect of Bifidobacteria intake on oral environment
Effect of Bifidobacteria intake on oral environment
Japan |
Chronic Periodontitis
Dental medicine |
Others
NO
To examine the effectiveness of Bifidobacteria intake on oral environment of chronic peridontitis patient during maintenance phase.
Efficacy
Exploratory
Others
Not applicable
Bacterial flora(Saliva, subgingival plaque)
Porphyromonas gingivalis, Treponema denticola, Tannerella forsythensis
(Observation period; 4 months)
Ig A (Saliva)
Probing pocket depth
Bleeding on probing
Gingival index
Interventional
Parallel
Randomized
Individual
Single blind -investigator(s) and assessor(s) are blinded
Placebo
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
3
Treatment
Food |
Bifidobacterium containing yogurt intake once a day for 8 weeks
Bifidobacterium non-containing yogurt intake once a day for 8 weeks
Sham control
40 | years-old | <= |
Not applicable |
Male and Female
Chronic Periodontitis
Maintenance phase
Probing pocket depths 5mm<=, =>7mm
Patients with serious disease
Allergy in food (especially dairy product)
Smoker
Lactating period
Pregnant
Antibiotics intake during 3 months
Antiplatelet agent intake
Yogurt, fermented milk drink and intestinal drug intake more than three times a week during 3 months
Participated in other clinical trials during one month
Drugs, supplements and foods which affect the result of the trial
30
1st name | |
Middle name | |
Last name | Yuichi Izumi |
Tokyo Medical and Dental University
Department of Periodontology
1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan
03-5803-5488
y-izumi.peri@tmd.ac.jp
1st name | |
Middle name | |
Last name | Tatsuya Akizuki |
Tokyo Medical and Dental University
Department of Periodontology
1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan
03-5803-5488
akizuki.peri@tmd.ac.jp
Tokyo Medical and Dental University
Meiji Corporation
Profit organization
Japan
NO
2017 | Year | 01 | Month | 15 | Day |
Unpublished
Terminated
2016 | Year | 11 | Month | 25 | Day |
2017 | Year | 01 | Month | 15 | Day |
2016 | Year | 11 | Month | 25 | Day |
2018 | Year | 03 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028762
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