Unique ID issued by UMIN | UMIN000025026 |
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Receipt number | R000028801 |
Scientific Title | Cognitive effects of adjunctive perampanel in patients with refractory epilepsy: an open-label, comparative study |
Date of disclosure of the study information | 2016/12/01 |
Last modified on | 2020/03/01 10:43:54 |
Cognitive effects of adjunctive perampanel in patients with refractory epilepsy: an open-label, comparative study
Cognitive effects of perampanel
Cognitive effects of adjunctive perampanel in patients with refractory epilepsy: an open-label, comparative study
Cognitive effects of perampanel
Japan |
Epilepsy
Neurology |
Others
NO
To evaluate cognitive effects of adjunctive perampanel in patients with refractory epilepsy
Safety,Efficacy
Changes of cognitive assessment scores from baseline after 48 weeks
Seizure frequency
Adverse events
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
2
Treatment
Medicine |
Patients are treated with perampanel for 48 weeks.
Patients are treated with other antiepileptic drugs for 48 weeks.
20 | years-old | <= |
Not applicable |
Male and Female
Patients had at least one partial seizure during the previous 3 months, despite a stable regimen of 1 or more antiepileptic drugs.
1. Pregnant or breast feeding
2. Simple partial seizure without motor symptoms
3. Primary generalized epilepsy
4. Psychiatric disorders
5. Unstable coronary heart disease
6. Drug and alcohol abuse
7. Surgical indication
8. Difficult to make decisions about participation due to severe cognitive impairment
50
1st name | |
Middle name | |
Last name | Kazuo Yamashiro |
Juntendo University School of Medicine
Department of Neurology
2-1-1 Hongo, Bukyo-ku, Tokyo
03-3813-3111
kazuo-y@juntendo.ac.jp
1st name | |
Middle name | |
Last name | Kazuo Yamashiro |
Juntendo University School of Medicine
Department of Neurology
2-1-1 Hongo, Bukyo-ku, Tokyo
03-3813-3111
kazuo-y@juntendo.ac.jp
Department of Neurology, Neurosurgery, Juntendo University School of Medicine
Department of Neurology, Neurosurgery, Juntendo University School of Medicine
Self funding
NO
順天堂大学医学部付属順天堂医院(東京都)
2016 | Year | 12 | Month | 01 | Day |
Unpublished
Terminated
2016 | Year | 10 | Month | 18 | Day |
2016 | Year | 10 | Month | 18 | Day |
2017 | Year | 01 | Month | 04 | Day |
2018 | Year | 11 | Month | 30 | Day |
2016 | Year | 11 | Month | 28 | Day |
2020 | Year | 03 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028801
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