Unique ID issued by UMIN | UMIN000025067 |
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Receipt number | R000028839 |
Scientific Title | Quantitative evaluation of T1 shortening in myocardium and left ventricle cavity by three different macrocyclic gadolinium based contrast agents |
Date of disclosure of the study information | 2016/12/01 |
Last modified on | 2021/03/25 09:20:37 |
Quantitative evaluation of T1 shortening in myocardium and left ventricle cavity by three different macrocyclic gadolinium based contrast agents
Quantitative evaluation of T1 shortening in heart by three different gadolinium based contrast agents
Quantitative evaluation of T1 shortening in myocardium and left ventricle cavity by three different macrocyclic gadolinium based contrast agents
Quantitative evaluation of T1 shortening in heart by three different gadolinium based contrast agents
Japan |
Heart disease
Cardiology | Radiology |
Others
NO
Late gadolinium enhancement (LGE) is widely used for clinical cardiac magnetic resonance imaging (CMR). Because LGE employs inversion recovery (IR) sequences, it would be sensitive for the difference in T1 relaxation times between normal myocardium and cardiac lesions. The aim of this study is to investigate the effect of three different macrocyclic gadolinium-based contrast agents (mGBCA) on T1 shortening in the myocardium and left ventricle (LV).
Others
Assessment of the ability to enhance by contrast agents for magnetic resonance imaging
Not applicable
T1 mapping was conducted using modified look-locker inversion recovery (MOLLI) sequences to measure the T1 relaxation time values of the myocardium and LV (1). Regions of Interest were drawn on the short axis images of areas of the myocardium without lesion involvement, at the LV septal/inferior walls, and in the LV cavity. An inversion scout sequence was also acquired seven min after mGBCA administration. Null points were defined as the inversion times (TI) that showed the lowest intensities of the myocardium and LV in each patient. The biological parameters of ejection fraction, estimated glomerular filtration rate, hematocrit, and heart rate were also compared across the three groups.
Others,meta-analysis etc
20 | years-old | < |
Not applicable |
Male and Female
Patients who underwent cardiac magnetic resonance imaging with T1 mapping before and after administration of gaddolinium contrast agents
- Examinations without T1 mapping sequence
- Diffuse myocardial lesion
40
1st name | Nakajima |
Middle name | |
Last name | Takahito |
Gunma University
Diagnostic Radiology and Nuclear Medicine
3718911
3-39-22, Showa, Maebashi, Gunma, Japan
027-220-8401
sojin@gunma-u.ac.jp
1st name | Nakajima |
Middle name | |
Last name | Takahito |
Gunma University Hospital
Diagnostic Radiology and Nuclear Medicine
3718911
3-39-22, Showa, Maebashi, Gunma, Japan
027-220-8401
sojin@gunma-u.ac.jp
Gunma University
Gunma University
Other
Gunma University
3-39-22, Showa, Maebashi, Gunma, Japan
+81272208401
sojin@gunma-u.ac.jp
NO
2016 | Year | 12 | Month | 01 | Day |
Unpublished
50
No longer recruiting
2015 | Year | 04 | Month | 01 | Day |
2015 | Year | 03 | Month | 26 | Day |
2015 | Year | 04 | Month | 01 | Day |
2022 | Year | 03 | Month | 31 | Day |
Plans for publications and presentations
2016 | Year | 11 | Month | 30 | Day |
2021 | Year | 03 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000028839
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