Unique ID issued by UMIN | UMIN000025427 |
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Receipt number | R000029269 |
Scientific Title | Study on efficacy and safety of combination treatment with febuxostat and inosine for patients with heart failure |
Date of disclosure of the study information | 2017/02/26 |
Last modified on | 2017/05/09 13:25:29 |
Study on efficacy and safety of combination treatment with febuxostat and inosine for patients with heart failure
Effect of febuxostat and inosine on heart failure
Study on efficacy and safety of combination treatment with febuxostat and inosine for patients with heart failure
Effect of febuxostat and inosine on heart failure
Japan |
heart failure
Cardiology |
Others
NO
Examine efficacy and safety of simultaneous administration of febuxostat and inosine for patients with heart failure.
Safety,Efficacy
Difference of serum BNP between before and after the treatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Administration of febuxostat 20 mg and inosine 500 mg twice a day for 14 days
20 | years-old | <= |
80 | years-old | >= |
Male and Female
1. Patients with 20 to 80 years of age
2. Patients with mild or moderate heart failure
3. Those who have the capacity to consent and consented with free will, after sufficient explanation of the purpose and contents of this study, to participate in the study with written document.
4. Patients whose BNP measured within 2 months before the start of the drug administration is higher than the normal range.
1. Subject who has or had hypersensitivity, idiosyncracy (allergy) to drug.
2. Subjects taking azathioprine or mercaptopurine
3. Subject who has or had renal function disorder.
4. Subject with a history of gout, hyperuricemia or urolithiasis.
5. Patients who changed therapeutic drugs and treatment methods within 1 month before administration of test drugs
6. Subject who was judged not to be appropriate by the principal investigator or sub investigators by other reasons.
6
1st name | |
Middle name | |
Last name | Naoyuki Kamatani |
Tsukuba International Clinical Pharmacology Clinic
Doctors' office
1-21-16 Kan-nondai Tsukuba City, Ibaraki Prefecture
029-839-1150
kamatani@msb.biglobe.ne.jp
1st name | |
Middle name | |
Last name | Masanori Suzuki |
Tsukuba International Clinical Pharmacology Clinic
Division for Volunteers
1-21-16 Kan-nondai Tsukuba City, Ibaraki Prefecture
029-839-1150
m-suzuki@tsukuba-icp.jp
Tsukuba International Clinical Pharmacology Clinic
StaGen Co. LTD
Profit organization
NO
2017 | Year | 02 | Month | 26 | Day |
Unpublished
Completed
2016 | Year | 12 | Month | 07 | Day |
2016 | Year | 12 | Month | 09 | Day |
2017 | Year | 05 | Month | 09 | Day |
2016 | Year | 12 | Month | 27 | Day |
2017 | Year | 05 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000029269
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