Unique ID issued by UMIN | UMIN000025495 |
---|---|
Receipt number | R000029339 |
Scientific Title | Intervention to improve the appropriate use of polypharmacy for older patients with hip fracture: an observational study |
Date of disclosure of the study information | 2017/01/02 |
Last modified on | 2018/01/09 13:51:07 |
Intervention to improve the appropriate use of polypharmacy for older patients with hip fracture: an observational study
Intervention to improve the appropriate use of polypharmacy for older patients with hip fracture
Intervention to improve the appropriate use of polypharmacy for older patients with hip fracture: an observational study
Intervention to improve the appropriate use of polypharmacy for older patients with hip fracture
Japan |
Hip fracture
Geriatrics | Orthopedics |
Others
NO
This study aims to evaluate the effectiveness of an intervention to improve appropriate polypharmacy for elderly patients with hip fracture.
Efficacy
The primary composite outcome was death or the first occurrence of any new fracture
Secondary outcomes were death, any new fractures, cardiovascular events, delirium, adverse drug events, in-hospital infections, or unplanned hospital admission for any reason.
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Treatment
Medicine |
The intervention consisted of an assessment of the appropriateness of polypharmacy and deprescribing any unnecessary medications by internal medicine physicians during the patients' hospital stay
We used hip fracture patients prescribed five or more medications at admission who pharmacist could not contact or rejected to receive the intervention for polypharmacy as a control group
65 | years-old | <= |
120 | years-old | >= |
Male and Female
all consecutive patients aged 65 years or more who were admitted to the hospital for hip fracture and who were prescribed five or more than medications at admission
Patients with hip fracture due to metastatic bone cancer were excluded
150
1st name | |
Middle name | |
Last name | Junpei Komagamine |
Tochigi Medical Center
Internal medicine
1-10-37, Nakatomatsuri, Utsunomiya, Tochigi 320-8580, Japan
028-622-5241
jkomagamine@tochigi-mc.jp
1st name | |
Middle name | |
Last name | Junpei Komagamine |
Tochigi Medical Center
Internal medicine
1-10-37, Nakatomatsuri, Utsunomiya, Tochigi 320-8580, Japan
028-622-5241
jkomagamine@tochigi-mc.jp
Tochigi Medical Center
Self funding
Self funding
NO
2017 | Year | 01 | Month | 02 | Day |
Published
https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-017-0681-3
A total of 164 patients were included in the study. The primary composite outcome occurred in 35 patients. No significant differences in the primary composite outcome were found between the intervention and usual care groups (7 in the intervention group and 28 in the usual care group, odds ratio 1.04, 95% CI 0.41-2.65; p?=?1.00).
Main results already published
2016 | Year | 09 | Month | 26 | Day |
2016 | Year | 09 | Month | 26 | Day |
Cases will be included retrospectively if the admission date of patients was after 1 January 2015
2017 | Year | 01 | Month | 02 | Day |
2018 | Year | 01 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000029339
Research Plan | |
---|---|
Registered date | File name |
2017/01/02 | polypharmacyと股関節骨折 研究計画書 20160926改訂.docx |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |