Unique ID issued by UMIN | UMIN000026437 |
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Receipt number | R000030370 |
Scientific Title | Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism |
Date of disclosure of the study information | 2017/04/01 |
Last modified on | 2023/03/12 11:08:29 |
Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism
Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism
Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism
Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism
Japan |
acute pulmonary thromboembolism
Cardiology |
Others
NO
To evaluate the developing risk of chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after ocurring acute pulmonary thromboembolism
Others
Prognosis of acute pulmonary thromboembolism
The developing risk of chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after one year ocurring acute pulmonary thromboembolism
1) developing risk of chronic pulmonary thromboembolism
2) developing risk of chronic thromboembolic pulmonary hypertension
3) recurrence of symptomatic acute pulmonary embolism
4)all cause death, cardiovascular death, non-cardiovascular death
5) incidence of bleeding
6) comparison of baseline characteristics
7) comparison among the treatments
8) trend of coagulation markers
Observational
16 | years-old | <= |
Not applicable |
Male and Female
1) patients with acute symptomatic pulmonary thromboembolism diagnosed by pulmonary arterial contrast enhanced CT, pulmonary angiography or ventilation/perfusion lung scan.
2) 16 years-old or older
3) obtained informed consent from patient
1) contrast medium allergy
2) eGFR lower than 30 mL/min/1.73m2
3) pregnancy
100
1st name | Shiro |
Middle name | |
Last name | Adachi |
Nagoya University Hospital
Department of Cardiology
466-8560
65 Tsurumai-cho, Shouwa-ku, Nagoya , Japan
+81-52-744-2150
takahisa@med.nagoya-u.ac.jp
1st name | Yoshihisa |
Middle name | |
Last name | Nakano |
Nagoya University Graduate School of Medicine
Department of Cardiology
466-8560
65 Tsurumai-cho, Shouwa-ku, Nagoya , Japan
+81-52-744-2150
okumura0607@med.nagoya-u.ac.jp
Nagoya University Graduate School of Medicine, Department of Cardiology
none
Self funding
Human Research Ethics Committees of Nagoya University Hospital
65 Tsurumai-cho, Shouwa-ku, Nagoya , Japan
052-744-2423
ethics@med.nagoya-u.ac.jp
NO
2017 | Year | 04 | Month | 01 | Day |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303750/
Partially published
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303750/
52
Fifty-two patients were enrolled. Two patients(3.8%)developed chronic thromboembolic pulmonary hypertension. A total of 43 patients completed evaluation at 1 year, among whom (74%) had residual thrombi, with a median modified CT obstruction index (mCTOI) of 10.7%. The tricuspid regurgitation pressure gradient 60 mmHg or over and left ventricular end-diastolic dimension at diagnosis were significantly related to mCTOI at 1 year.
2022 | Year | 09 | Month | 10 | Day |
patients with acute pulmonary thromboembolism
patients diagnosed with acute PE were recruited and examinations were conducted at 1 month, 6 months, and 1 year. Especially at 1 year, patients were evaluated multifacetedly, including by laboratory tests, quality-of-life, 6-min walking test, and enhanced CT.
All cause death was obsreved in two patients, and major bleeding in two patients.
residual thrombi one year after acute pulmonary thromboembolism
Completed
2017 | Year | 01 | Month | 01 | Day |
2017 | Year | 03 | Month | 16 | Day |
2017 | Year | 04 | Month | 01 | Day |
2020 | Year | 12 | Month | 31 | Day |
2022 | Year | 12 | Month | 31 | Day |
none
2017 | Year | 03 | Month | 07 | Day |
2023 | Year | 03 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030370
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