Unique ID issued by UMIN | UMIN000027485 |
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Receipt number | R000030383 |
Scientific Title | Efficacy and safety of injectable quinine for the treatment of malaria in Japan |
Date of disclosure of the study information | 2017/05/25 |
Last modified on | 2019/11/25 13:03:15 |
Efficacy and safety of injectable quinine for the treatment of malaria in Japan
Efficacy and safety of injectable quinine for the treatment of malaria in Japan
Efficacy and safety of injectable quinine for the treatment of malaria in Japan
Efficacy and safety of injectable quinine for the treatment of malaria in Japan
Japan |
malaria
Infectious disease |
Others
NO
To treat severe malaria patients and malaria patients who cannot take oral anti-malaria drugs with injectable quinine.
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
cure rate
1) time required for fever disappearance
2) parasite clearance time
3) recurrence after 28 days of treatment
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Administer injectable quinine for the treatment of malaria (8.3 mg base/kgBW, 16.6 mg for loading)in 500 mL of 5% glucose or physiological saline, for upto 7 days.
Not applicable |
Not applicable |
Male and Female
Severe malaria patients or malaria patients who cannot take oral anti-malaria drugs, who agree to join the study.
1) Patients who are allergic to injectable quinine or related compounds
2) Patients who do not agree to give written informed consent
3) Patients principal who investigator considers inappropriate
33
1st name | Maruyama |
Middle name | |
Last name | Haruhiko |
University of Miyazaki
Faculty of Medicine
889-1692
5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki, Japan
0985-85-0990
hikomaru@med.miyazaki-u.ac.jp
1st name | Mizoguchi |
Middle name | |
Last name | Ayami |
University of Miyazaki
Faculty of Medicine
889-1692
5200 Kihara, Kiyotake-Cho, Miyazaki City, Miyazaki, Japan
0985-85-0990
ayami_mizoguchi@med.miyazaki-u.ac.jp
University of Miyazaki
Japan Agency for Medical Research and Development (AMED)
Japanese Governmental office
Hospital of University of Miyazaki Clinical Research Support Center
KIhara 5200, Kiyotake-cho, Miyazaki, Miyazaki 889-1692
0985-85-9403
rinken@med.miyazaki-u.ac.jp
NO
2017 | Year | 05 | Month | 25 | Day |
Unpublished
Completed
2017 | Year | 04 | Month | 05 | Day |
2017 | Year | 06 | Month | 16 | Day |
2017 | Year | 07 | Month | 01 | Day |
2019 | Year | 03 | Month | 18 | Day |
2017 | Year | 05 | Month | 25 | Day |
2019 | Year | 11 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030383
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