UMIN-CTR Clinical Trial

Unique ID issued by UMIN UMIN000026948
Receipt number R000030908
Scientific Title Screening for adiponectin secretion using Adipose-derived stem cells in metabolic syndrome
Date of disclosure of the study information 2017/04/11
Last modified on 2019/01/07 11:50:16

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Basic information

Public title


Screening for adiponectin secretion using Adipose-derived stem cells in metabolic syndrome

Acronym


Screening for adiponectin secretion using Adipose-derived stem cells in metabolic syndrome

Scientific Title


Screening for adiponectin secretion using Adipose-derived stem cells in metabolic syndrome

Scientific Title:Acronym


Screening for adiponectin secretion using Adipose-derived stem cells in metabolic syndrome

Region

Japan


Condition

Condition

obesity

Classification by specialty

Endocrinology and Metabolism Gastrointestinal surgery

Classification by malignancy

Others

Genomic information

NO


Objectives

Narrative objectives1

Screening of adiponectin secretion-promoting drugs / foods with adipose derived stem cells (ADSC) that isolated from surgically collected adipose tissue of obese.

Basic objectives2

Bio-availability

Basic objectives -Others


Trial characteristics_1


Trial characteristics_2


Developmental phase



Assessment

Primary outcomes

Adiponectin level in adipocyte culture supernatant

Key secondary outcomes



Base

Study type

Observational


Study design

Basic design


Randomization


Randomization unit


Blinding


Control


Stratification


Dynamic allocation


Institution consideration


Blocking


Concealment



Intervention

No. of arms


Purpose of intervention


Type of intervention


Interventions/Control_1


Interventions/Control_2


Interventions/Control_3


Interventions/Control_4


Interventions/Control_5


Interventions/Control_6


Interventions/Control_7


Interventions/Control_8


Interventions/Control_9


Interventions/Control_10



Eligibility

Age-lower limit

20 years-old <=

Age-upper limit

85 years-old >

Gender

Male and Female

Key inclusion criteria

1. over BMI25kg/m2
2. Patient undergoing obesity surgery at Osaka University hospital
3. Patient who got written consent from himself / herself

Key exclusion criteria

1. <20 years old
2. Have severe infection
3. pregnant
4. The doctor in charge judges it as inappropriate as a subject.

Target sample size

60


Research contact person

Name of lead principal investigator

1st name
Middle name
Last name Toshinori ITO

Organization

Osaka University Graduate School of Medicine

Division name

Department of Integrative Medicine

Zip code


Address

2-2, Yamadaoka, Suita, OSAKA

TEL

06-6879-3498

Email

mikity@cam.med.osaka-u.ac.jp


Public contact

Name of contact person

1st name
Middle name
Last name Miki Sakaue

Organization

Osaka University Graduate School of Medicine

Division name

Department of Integrative Medicine

Zip code


Address

2-2, Yamadaoka, Suita, OSAKA

TEL

06-6879-3498

Homepage URL


Email

mikity@cam.med.osaka-u.ac.jp


Sponsor or person

Institute

Department of Integrative Medicine, Osaka University Graduate School of Medicine

Institute

Department

Personal name



Funding Source

Organization

Department of Integrative Medicine, Osaka University Graduate School of Medicine

Organization

Division

Category of Funding Organization

Self funding

Nationality of Funding Organization



Other related organizations

Co-sponsor


Name of secondary funder(s)



IRB Contact (For public release)

Organization


Address


Tel


Email



Secondary IDs

Secondary IDs

NO

Study ID_1


Org. issuing International ID_1


Study ID_2


Org. issuing International ID_2


IND to MHLW



Institutions

Institutions



Other administrative information

Date of disclosure of the study information

2017 Year 04 Month 11 Day


Related information

URL releasing protocol


Publication of results

Unpublished


Result

URL related to results and publications


Number of participants that the trial has enrolled


Results


Results date posted


Results Delayed


Results Delay Reason


Date of the first journal publication of results


Baseline Characteristics


Participant flow


Adverse events


Outcome measures


Plan to share IPD


IPD sharing Plan description



Progress

Recruitment status

Completed

Date of protocol fixation

2015 Year 08 Month 12 Day

Date of IRB


Anticipated trial start date

2015 Year 08 Month 25 Day

Last follow-up date


Date of closure to data entry


Date trial data considered complete


Date analysis concluded



Other

Other related information

This study will search for secretagogues of adiponectin in vitro.


Management information

Registered date

2017 Year 04 Month 11 Day

Last modified on

2019 Year 01 Month 07 Day



Link to view the page

Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000030908


Research Plan
Registered date File name

Research case data specifications
Registered date File name

Research case data
Registered date File name