Unique ID issued by UMIN | UMIN000027134 |
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Receipt number | R000031089 |
Scientific Title | Does the response in urine output to a small dose of furosemide predict organ failure after achievement of negative fluid balance in acute respiratory failure ? |
Date of disclosure of the study information | 2017/04/27 |
Last modified on | 2021/02/19 23:21:52 |
Does the response in urine output to a small dose of furosemide predict organ failure after achievement of negative fluid balance in acute respiratory failure ?
Furosemide stress test to predict tolerance to negative fluid balance
Does the response in urine output to a small dose of furosemide predict organ failure after achievement of negative fluid balance in acute respiratory failure ?
Furosemide stress test to predict tolerance to negative fluid balance
Japan |
acute respiratory failure
Intensive care medicine |
Others
NO
The objective was to evaluate the ability of a furosemide stress test to predict tolerance of negative fluid balance (NFB) in patients with acute respiratory failure.
Efficacy
Poor tolerance of negative fluid balance in 24 hours
Poor tolerance of negative fluid balance was evaluated by the development of hypotension, or the need for fluid expansion, or the need for vasopressors.
When NFB was induced by furosemide, acute kidney injury was also considered as a criterion of poor tolerance.
Observational
18 | years-old | <= |
Not applicable |
Male and Female
Mechanically ventilated patients who have been endotracheally intubated for respiratory failure with hemodynamic stability were included
(1) baseline estimated glomerular filtration rate (eGFR) <30 ml/minute/1.73m2;
(2) known pregnancy;
(3) evidence of obstructive uropathy (for example, hydro-ureter)
(4) patients with allergy or known sensitivity to loop diuretics
(5) achievement of AKIN stage III criteria;
(6) evidence of volume depletion at the time of furosemide administration
60
1st name | |
Middle name | |
Last name | JUN KATAOKA |
Tokyo Bay Urayasu Ichikawa Medical Center
Department of Critical Care Medicine
3-4-32, Todaijima, Urayasu-shi, Japan
047-351-3101
rdcyc910@yahoo.co.jp
1st name | |
Middle name | |
Last name | JUN KATAOKA |
Tokyo Bay Urayasu Ichikawa Medical Center
Department of Critical Care Medicine
3-4-32, Todaijima, Urayasu-shi, Japan
047-351-3101
rdcyc910@yahoo.co.jp
Tokyo Bay Urayasu Ichikawa Medical Center
None
Self funding
NO
2017 | Year | 04 | Month | 27 | Day |
Unpublished
Completed
2016 | Year | 10 | Month | 01 | Day |
2016 | Year | 10 | Month | 01 | Day |
2016 | Year | 10 | Month | 01 | Day |
2018 | Year | 08 | Month | 31 | Day |
urine output
2017 | Year | 04 | Month | 26 | Day |
2021 | Year | 02 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031089
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