Unique ID issued by UMIN | UMIN000027585 |
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Receipt number | R000031353 |
Scientific Title | Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study |
Date of disclosure of the study information | 2017/06/19 |
Last modified on | 2019/06/25 17:36:06 |
Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study
Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study
(JFMC50-1701-C6)
Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study
Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study
(JFMC50-1701-C6)
Japan |
Colorectal Cancer
Gastroenterology | Gastrointestinal surgery |
Malignancy
NO
We investigate a reason for treatment termination of TFTD (such as RECIST PD, PD by imaging beyond RECIST PD, Clinical PD , adverse event, others) by a retrospective cohort study to find which type of cases can obtain long-term survival by TFTD.
Safety,Efficacy
Exploratory
Others
Not applicable
We compare the difference of the overall survival by each reason (RECIST PD, PD by imaging beyond RECIST PD, Clinical PD , adverse event, others) for termination of TFTD.
Relationship between overall survival and the therapy prior TFTD
Relationship between overall survival and the therapy after TFTD
Observational
20 | years-old | <= |
Not applicable |
Male and Female
<1st registration>
The metastatic colorectal cancer patients treated with TFTD monotherapy from July 1, 2014 to September 30, 2016.
<2nd registration>
1)Patient with ECOG-PS 0 or 1 at the start of TFTD therapy.
2)Patient older than 19 at the time of registration.
3)Patient who receives TFTD at an initial dose of more than -10mg/day/body.
1)Patients with active double cancer. Carcinoma in situ (intraepithelial carcinoma) or the intramucosal carcinoma equivalent lesion which are concurrent double cancers and heterochronous double cancers within five years, and the investigator judged to cure by topical treatment, are excluded as the double cancer.
2)Infectious disease to be treated.
3)History of severe comorbidities at the start of TFTD. (severe DM, heart failure over NYHA II degree, renal failure, liver failure etc.).
4)Brain metastasis with clinical symptom who need periodical medication (mannitol and steroid, anticonvulsant).
1200
1st name | |
Middle name | |
Last name | 1)EIJI OKI 2)KENTARO YAMAZAKI |
1)Graduate School of Surgery and Science Kyushu University 2)Shizuoka Cancer Center
1)Department of Surgery and Science 2)Division of Endoscopy & GI Oncology
1)3-1-1 Maidashi, Higashi-ku, Fukuoka City, FUKUOKA, 812-8585, Japan 2)1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, SHIZUOKA,411-8777, Japan
03-5627-7594
jfmc50@jfmc.or.jp
1st name | |
Middle name | |
Last name | EIJI OKI |
Graduate School of Surgery and Science Kyushu University
Department of Surgery and Science
3-1-1 Maidashi, Higashi-ku, Fukuoka City, FUKUOKA, 812-8585, Japan
092-642-5466
http://www.jfmc.or.jp
jfmc50@jfmc.or.jp
Japanese Foundation for Multidisciplinary Treatment of Cancer
TAIHO PHARMACEUTICAL CO.,LTD
Profit organization
NO
2017 | Year | 06 | Month | 19 | Day |
Unpublished
Completed
2017 | Year | 02 | Month | 16 | Day |
2017 | Year | 02 | Month | 16 | Day |
2017 | Year | 06 | Month | 19 | Day |
2018 | Year | 02 | Month | 28 | Day |
Evaluation of outcome and reason of treatment termination of TFTD for colorectal cancer : A retrospective cohort study
<1st registration>
The metastatic colorectal cancer patients treated with TFTD monotherapy from July 1, 2014 to September 30, 2016.
<2nd registration>
1)Patient with ECOG-PS 0 or 1 at the start of TFTD therapy.
2)Patient older than 19 at the time of registration.
3)Patient who receives TFTD at an initial dose of more than -10mg/day/body.
2017 | Year | 06 | Month | 01 | Day |
2019 | Year | 06 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031353
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