Unique ID issued by UMIN | UMIN000029164 |
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Receipt number | R000031539 |
Scientific Title | A New Diagnostic Method for Thyroid Carcinoma Associated with Autoantibody against Cancer Specific Antigen |
Date of disclosure of the study information | 2017/09/15 |
Last modified on | 2023/03/21 14:46:25 |
A New Diagnostic Method for Thyroid Carcinoma Associated with Autoantibody against Cancer Specific Antigen
Autoantibody against Thyroid Carcinoma Specific Antigen
A New Diagnostic Method for Thyroid Carcinoma Associated with Autoantibody against Cancer Specific Antigen
Autoantibody against Thyroid Carcinoma Specific Antigen
Japan |
Thyroid Carcinoma
Medicine in general | Endocrinology and Metabolism | Endocrine surgery |
Oto-rhino-laryngology |
Malignancy
NO
To investigate a new diagnostic method associated with autoantibody against thyroid carcinoma
Safety,Efficacy
Confirmatory
Explanatory
Not applicable
To investigate the titer of autoantibody against thyroid carcinoma in 6 groups (progressive thyroid carcinoma, nonprogressive thyroid carcinoma, benign thyroid nodule, Graves' disease, chronic thyroiditis, and normal control)
1) To invastigate the change of titer in the treatment of thyroid carcinoma
2) To investigate the correlations between autoantibodies against thyroid carcinoma and clinical parameters including pathological diagnosis, cytological diagnosis, thyroid function test, thyroid autoantibodies, and imaging study
3) To investigate the safety including nonspecific antigen-antibody interaction
Observational
20 | years-old | <= |
90 | years-old | > |
Male and Female
1. Progressive thyroid carcinoma
UICC stage >2 thyroid carcinoma including papillary, follicular, and indifferenciated thyroid carcinoma
2. Inprogressive thyroid carcinoma
UICC stage 1 thyroid carcinoma including papillary and follicular thyroid carcinoma
3. Benign thyroid tumor
Disgnosed as benign by ultrasound and fine needle aspiration cytology
4. Graves' disease
Diagnosed by Guideline for the diagnosis of Graves' disease (JTA 2013)
5. Chronic thyroiditis
Diagnosed by Guideline for the diagnosis of Chronic thyroiditis (JTA 2013)
6. Normal control
Those who fulfill these 4 criteria
1) normal thyroid function
2) thyroid autoantibody (TgAb and/or TPOAb) negative
3) no thyroid nodule detected by ultrasound survey
4) no symptoms and signs were obtained and judged healthy by the researchers
1. Advanced thyroid carcinoma
1) history of malignant tumor in other organs
2) pregnant or suspected of pregnancy
3) others not suitable for entry
2. Inadvanced thyroid carcinoma
1) history of malignant tumor in other organs
2) pregnant or suspected of pregnancy
3) others not suitable for entry
3. Benign thyroid tumor
1) history of malignant tumor in other organs
2) pregnant or suspected of pregnancy
3) others not suitable for entry
4. Graves' disease
1) history of malignant tumor in other organs
2) post thyroidectomy
3) post I-131 ablation
4) pregnant or suspected of pregnancy
5) others not suitable for entry
5. Chronic thyroiditis
1) history of malignant tumor in other organs
2) post thyroidectomy
3) pregnant or suspected of pregnancy
4) others not suitable for entry
6. Normal control
1) history of malignant tumor in other organs
2) pregnant or suspected of pregnancy
3) others not suitable for entry
180
1st name | |
Middle name | |
Last name | Shoichiro Izawa |
Tottori University Hospital
Division of Endocrinology and Metabolism
36-1 Nishi-cho, Yonago
0859-38-6512
s-izawa@med.tottori-u.ac.jp
1st name | |
Middle name | |
Last name | Shoichiro Izawa |
Tottori University Hospital
Division of Endocrinology and Metabolism
36-1 Nishi-cho, Yonago
0859-38-6517
s-izawa@med.tottori-u.ac.jp
Tottori University Hospital
This study is supported by JSPS KAKENHI Grant number 16K21173
Japanese Governmental office
NO
2017 | Year | 09 | Month | 15 | Day |
Unpublished
Completed
2017 | Year | 07 | Month | 08 | Day |
2017 | Year | 08 | Month | 25 | Day |
2017 | Year | 09 | Month | 11 | Day |
2021 | Year | 12 | Month | 31 | Day |
2022 | Year | 03 | Month | 31 | Day |
2023 | Year | 03 | Month | 31 | Day |
None
2017 | Year | 09 | Month | 15 | Day |
2023 | Year | 03 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031539
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