Unique ID issued by UMIN | UMIN000027735 |
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Receipt number | R000031777 |
Scientific Title | The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method |
Date of disclosure of the study information | 2017/06/13 |
Last modified on | 2017/06/13 00:02:26 |
The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method
The time course of bronchoconstriction triggered cough reaction induced by Methacholine
The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method
The time course of bronchoconstriction triggered cough reaction induced by Methacholine
Japan |
cough variant asthma
Pneumology |
Others
NO
The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method
Safety
The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Diagnosis
Device,equipment |
day1 The measurement of cough response to bronchoconstriction induced by Methacholine using Astograph method
day2 The measurement of cough response to bronchoconstriction induced by Methacholine using Astograph method (Investigation the reproducibility)
In day2, we compare the concentration of lipid mediators in the exhaled breath condensate between before and after methacholine inhalation.
20 | years-old | <= |
Not applicable |
Male and Female
Male and female healthy subjects >= 20 years of age are eligible for inclusion.
No symptom and history of respiratory disease, cardiovascular disease, gastrointestinal disease, hepatobiliar-pancreatic disease, endocrine and metabolic disease, hematological and malignant disease, renal disease, neuromuscular disease, collagen disease, autoimmune disease, psychosomatic and mental disorder, chronic infectious disease, obstetric and gynecological disease, urological disease, cerebral nervous disease.
Key exclusion criteria were: tachyarrhythmia, heart failure; women of childbearing potential or of breast-feeding; mental disorder or psychiatric symptom; several medical conditions prohibiting partitipation.
15
1st name | |
Middle name | |
Last name | Johsuke Hara |
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Department of Respiratory Medicine
13-1 Takara-machi Kanazawa Ishikawa
076-265-2000
hara0728@gmail.com
1st name | |
Middle name | |
Last name | Johsuke Hara |
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Department of Respiratory Medicine
13-1 Takara-machi Kanazawa Ishikawa
076-265-2000
hara0728@gmail.com
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Other
NO
2017 | Year | 06 | Month | 13 | Day |
Unpublished
Preinitiation
2017 | Year | 06 | Month | 13 | Day |
2017 | Year | 06 | Month | 14 | Day |
2017 | Year | 06 | Month | 13 | Day |
2017 | Year | 06 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031777
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