Unique ID issued by UMIN | UMIN000027812 |
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Receipt number | R000031813 |
Scientific Title | Changes in skeletal muscle loss between cytotoxic chemotherapy and molecular targeted therapy in patients with advanced non-small cell lung cancer |
Date of disclosure of the study information | 2017/06/20 |
Last modified on | 2017/06/19 13:32:50 |
Changes in skeletal muscle loss between cytotoxic chemotherapy and molecular targeted therapy in patients with advanced non-small cell lung cancer
Changes in skeletal muscle loss between cytotoxic chemotherapy and molecular targeted therapy in patients with advanced non-small cell lung cancer
Changes in skeletal muscle loss between cytotoxic chemotherapy and molecular targeted therapy in patients with advanced non-small cell lung cancer
Changes in skeletal muscle loss between cytotoxic chemotherapy and molecular targeted therapy in patients with advanced non-small cell lung cancer
Japan |
Patients with pathologically proven Non-small cell lung cancer stage4
Pneumology |
Malignancy
NO
Clarifying to the changes in the skeletal muscle area pre- to post chemotherapy in patients receiving cytotoxic chemotherapy and in those receiving EGFR and ALK-TKI.
Efficacy
Exploratory
Pragmatic
Not applicable
Muscle mass was measured with a single cross-sectional area of the muscle at the third lumber vertebra (L3MA). To estimate skeletal muscle changes during chemotherapy, we set the following L3 muscle index (L3SMI) ratio: post L3SMI / pre L3SMI.
Observational
20 | years-old | <= |
90 | years-old | >= |
Male and Female
Pathologically confirmed NSCLC stage4 according to UICC TNM stage classification, the administration of first-line chemotherapy, and a clear before and after CT image (coverage of L2 and L3 vertebral body).
None
100
1st name | |
Middle name | |
Last name | Masamichi Mineshita |
St. Marianna University School of Medicine
Internal Medicine, Division of Respiratory Medicine
2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
044-977-8111
m-mine@marianna-u.ac.jp
1st name | |
Middle name | |
Last name | Kazutaka Kakinuma |
Internal Medicine
Division of Respiratory Medicine
2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan.
044-977-8111
k2kakinuma@marianna-u.ac.jp
St. Marianna University School of Medicine
None
Self funding
NO
2017 | Year | 06 | Month | 20 | Day |
Unpublished
No longer recruiting
2017 | Year | 05 | Month | 20 | Day |
2017 | Year | 05 | Month | 30 | Day |
None
2017 | Year | 06 | Month | 19 | Day |
2017 | Year | 06 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031813
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