Unique ID issued by UMIN | UMIN000027929 |
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Receipt number | R000031991 |
Scientific Title | The effect of exercise preconditioning with blood flow restriction on ischemia reperfusion injury and postoperative course after total knee arthroplasty. |
Date of disclosure of the study information | 2017/06/26 |
Last modified on | 2019/09/02 22:26:36 |
The effect of exercise preconditioning with blood flow restriction on ischemia reperfusion injury and postoperative course after total knee arthroplasty.
The effect of exercise preconditioning with blood flow restriction on ischemia reperfusion injury and postoperative course after total knee arthroplasty.
The effect of exercise preconditioning with blood flow restriction on ischemia reperfusion injury and postoperative course after total knee arthroplasty.
The effect of exercise preconditioning with blood flow restriction on ischemia reperfusion injury and postoperative course after total knee arthroplasty.
Japan |
Osteoarthritis of the knee
Rehabilitation medicine |
Others
NO
The purpose of this study is to clarify the effectiveness of exercise preconditioning with blood flow restriction in patients waiting for total knee arthroplasty.
Efficacy
The Primary outcome is quadriceps muscle strength. All patients included in the study are assessed 5 times: tests are performed 3 months and 1 week before surgery, 4 days, 1 month and 3 months after surgery.
The secondary outcomes are knee swelling, knee range of motion, performance test, knee injury and osteoarthritis outocome score, and Japanese knee osteoarthritis measure.
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Active
2
Treatment
Other |
The exercise contents of the intervention group are a squat, a forward lunge, bilateral leg extension with blood flow restriction and cycle ergometer training. These exercises are performed once a week for 8 weeks before surgery.
The exercise contents of the control group are a squat, a forward lunge, bilateral leg extension without blood flow restriction and cycle ergometer training. These exercises are performed once a week for 8 weeks before surgery.
60 | years-old | <= |
80 | years-old | > |
Male and Female
1. Japanese males and females
2. between 60 and 79 years old
3. primary knee osteoarthritis
4. radiographic severity classified using Kellgren-Lawrence System was grade 3 to grade 4
1. patients with serious heart disease and diabetes
2. history of rheumatoid arthritis, neurological disease, and peripheral artery disease
3. patients with abnormalities of blood coagulation and fibrinolysis
4. smoker
5. patients who cannot exercise due to knee pain
30
1st name | |
Middle name | |
Last name | Yusuke Kubo |
Kobori Orthopedic Clinic
Department of Rehabilitation Medicine
548-2 Nearaichou, Kita-ku, Hmamatsu City, Shizuoka
053-438-3133
yusuke.kubo11@gmail.com
1st name | |
Middle name | |
Last name | Yusuke Kubo |
Kobori Orthopedic Clinic
Department of Rehabilitation Medicine
548-2 Nearaichou, Kita-ku, Hmamatsu City, Shizuoka
053-438-3133
yusuke.kubo11@gmail.com
Kobori Orthopedic Clinic
None
Self funding
NO
2017 | Year | 06 | Month | 26 | Day |
Unpublished
Completed
2017 | Year | 04 | Month | 23 | Day |
2017 | Year | 04 | Month | 23 | Day |
2017 | Year | 06 | Month | 26 | Day |
2019 | Year | 07 | Month | 01 | Day |
2017 | Year | 06 | Month | 25 | Day |
2019 | Year | 09 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000031991
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