Unique ID issued by UMIN | UMIN000028157 |
---|---|
Receipt number | R000032006 |
Scientific Title | A study of the relationship between postoperative delirium and inflammatory markers. |
Date of disclosure of the study information | 2017/07/10 |
Last modified on | 2020/07/12 09:42:40 |
A study of the relationship between postoperative delirium and inflammatory markers.
Postoperative delirium and inflammatory markers
A study of the relationship between postoperative delirium and inflammatory markers.
Postoperative delirium and inflammatory markers
Japan |
Postoperative delirium
Gastrointestinal surgery | Psychiatry |
Malignancy
NO
We evaluate inflammatory markers which are thought to be related with the onset and severity of delirium on the patients who are participating in the clinical study carried out in our hospital named "Evaluation of the efficacy of yokukansan for postoperative delirium".
Safety,Efficacy
Confirmatory
The relationship between the presence/severity of delirium and inflammatory markers (NLRP3, IL-1beta, IL-6, IL-8, IL-18, TNF -alpha in serum or mononuclear leukocyte), and the effects of yokukansan.
Correlation between the inflammatory markers
Association between safety, harmful phenomenon and inflammatory markers
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
2
Prevention
Medicine |
Yokukansan group take 2.5 g of yokukansan before every meal from the morning of the previous day until the morning of the operation day. After surgery, patients start taking yokukansan as soon as possible and take until the 3rd postoperative day. Blood is collected on the day before operation, and first and third day after the operation.
Control group take 2.5 g of anchusan before every meal from the morning of the previous day until the morning of the operation day. After surgery, patients start taking anchusan as soon as possible and take until the 3rd postoperative day. Blood is collected on the day before operation, and first and third day after the operation.
75 | years-old | <= |
Not applicable |
Male and Female
The man and woman who agrees to the participation of the study named "Evaluation of the efficacy of yokukansan for postoperative delirium".
None.
100
1st name | Masaaki |
Middle name | |
Last name | Iwata |
Tottori University Hospital
Division of Neuropsychiatry
683-0826
36-1 Nishi-cho, Yonago, Tottori
0859-38-6547
yanmasa@f8.dion.ne.jp
1st name | Iwata |
Middle name | |
Last name | Masaaki |
Tottori University Hospital
Division of Neuropsychiatry
683-0826
36-1 Nishi-cho, Yonago, Tottori
0859-38-6547
yanmasa@f8.dion.ne.jp
Tottori University Hospital
Tottori University Hospital
Other
Tottori University Hospital Institutional Review Board
36-1 Nishi-cho, Yonago, Tottori
0859-33-1111
crsc@ml.med.tottori-u.ac.jp
NO
2017 | Year | 07 | Month | 10 | Day |
Unpublished
20
Open public recruiting
2017 | Year | 06 | Month | 06 | Day |
2017 | Year | 06 | Month | 08 | Day |
2017 | Year | 07 | Month | 12 | Day |
2022 | Year | 05 | Month | 30 | Day |
2017 | Year | 07 | Month | 10 | Day |
2020 | Year | 07 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032006
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |