Unique ID issued by UMIN | UMIN000027990 |
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Receipt number | R000032057 |
Scientific Title | Proteasome inhibitor for relapsed pediatric acute lymphoblastic leukemia following allogeneic stem cell transplantation |
Date of disclosure of the study information | 2017/06/30 |
Last modified on | 2017/06/29 12:00:16 |
Proteasome inhibitor for relapsed pediatric acute lymphoblastic leukemia following allogeneic stem cell transplantation
Proteasome inhibitor for relapsed pediatric acute lymphoblastic leukemia following HCT
Proteasome inhibitor for relapsed pediatric acute lymphoblastic leukemia following allogeneic stem cell transplantation
Proteasome inhibitor for relapsed pediatric acute lymphoblastic leukemia following HCT
Japan |
pediatric acute lymphoblastic leukemia
Hematology and clinical oncology |
Malignancy
NO
To provide a therapy effective against a case of relapsed pediatric acute lymphoblastic leukemia following HCT that can extend a life prognosis
Efficacy
Others
Others
Not applicable
Hematological remission on day 29
Examination of safety based on CTCAE ver. 4.0 on day 29
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
1
Treatment
Medicine |
Bortezomib, (1.3mg/m2) : day 1, 4, 8, 11
Vincristine, (1.5mg/m2): day 1, 8, 15, 22
Doxorubicin, (60mg/m2): day 1
Dexamethasone, (10mg/m2/day): day 1-14
L-asparaginase, (10000U/m2): day 2, 5, 8, 11, 15, 18, 22, 25
2 | years-old | <= |
2 | years-old | > |
Male
No active infection, performance status is required for more than 50 on Lansky score is eligible.
Not meeting the requirement the above is excluded.
1
1st name | |
Middle name | |
Last name | Nibuyuki Hyakuna |
University of Ryukyus, Hospital
Department of Pediatrics
Uehara 207, Nishihara cho, Okinawa
098-895-3331
hyakunan@med.u-ryukyu.ac.jp
1st name | |
Middle name | |
Last name | Satoru Hamada |
University of Ryukyus, Hospital
Department of Pediatrics
Uehara 207, Nishihara cho, Okinawa
098-895-3331
shamada@med.u-ryukyu.ac.jp
University of Ryukyus, Hospital
University of Ryukyus, Hospital
Other
NO
2017 | Year | 06 | Month | 30 | Day |
Unpublished
Preinitiation
2017 | Year | 06 | Month | 23 | Day |
2017 | Year | 06 | Month | 23 | Day |
2017 | Year | 06 | Month | 29 | Day |
2017 | Year | 06 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032057
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