Unique ID issued by UMIN | UMIN000028203 |
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Receipt number | R000032125 |
Scientific Title | Usefulness of kestose with Inflammatory Bowel Disease |
Date of disclosure of the study information | 2017/07/12 |
Last modified on | 2022/04/27 20:48:48 |
Usefulness of kestose with Inflammatory Bowel Disease
Treatment with kestose for Inflammatory Bowel Disease
Usefulness of kestose with Inflammatory Bowel Disease
Treatment with kestose for Inflammatory Bowel Disease
Japan |
Inflammatory Bowel Disease
Gastroenterology | Endocrinology and Metabolism |
Others
NO
To evaluate the efficacy of kestose in the patients with Inflammatory Bowel Disease
Efficacy
Improvement of clinical condition in patients with Inflammatory Bowel Disease
1.Changes of short-chain fatty acid (Butyric acid,Acetic acid,Propionic acid etc.)
2.changes of endoscopic score
3.changes of concentration of carprotectin in feces
4.Changes of pathologic and metabolic marker (T.Cho, LDL-Cho, HDL-Cho, TG, FFA, ferritin,HbA1c,CRP,TP,ALB etc.)
5.Correlation of gut microbiota and therapeutic effect
6.Changes of body weight and BMI
7.Metabolome and protein analysis of metabolite in feces
8.Changes of bile acid
9.Correlation between expiratory noble gases, gut microbiota and NAFLD/NASH
10.Correlation between usefulness of kestose and disease prognosis in the patients with Inflammatory Bowel Disease
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
Central registration
2
Treatment
Food |
kestose
placebo
20 | years-old | <= |
80 | years-old | >= |
Male and Female
Patients diagnosed as Inflammatory Bowel Disease(ulcerative colitis,crohn disease)
1.Women with pregnancy or possible pregnancy
2.Patients with severe renal failure and heart failure
3.Patient who is considered to be inappropriate for entry into the trial by the investigator
4.Medical doctors decided the patients are inappropriate.
40
1st name | |
Middle name | |
Last name | Yoshiki Hirooka |
Nagoya University Hospital
Department of Endoscopy
65 tsurumai-cho, Showa-ku, Nagoya
+81-52-744-2602
hirooka@med.nagoya-u.ac.jp
1st name | |
Middle name | |
Last name | Keisaku yamada |
Nagoya University Hospital
Department of Gastroenterology and Hepatology
65 tsurumai-cho, Showa-ku, Nagoya
+81-52-744-2602
kei-yama@med.nagoya-u.ac.jp
Nagoya University Hospital
B Food Science Co.,Ltd.
Profit organization
NO
2017 | Year | 07 | Month | 12 | Day |
Unpublished
Completed
2017 | Year | 07 | Month | 08 | Day |
2017 | Year | 09 | Month | 07 | Day |
2018 | Year | 04 | Month | 06 | Day |
2021 | Year | 09 | Month | 01 | Day |
2017 | Year | 07 | Month | 12 | Day |
2022 | Year | 04 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032125
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