Unique ID issued by UMIN | UMIN000028165 |
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Receipt number | R000032244 |
Scientific Title | Influence of ingestion of eicosapentaenoic acid-rich fish oil on muscle stiffness following eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial |
Date of disclosure of the study information | 2017/07/20 |
Last modified on | 2020/01/11 05:09:48 |
Influence of ingestion of eicosapentaenoic acid-rich fish oil on muscle stiffness following eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial
Trial of eicosapentaenoic acid on muscle stiffness
Influence of ingestion of eicosapentaenoic acid-rich fish oil on muscle stiffness following eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial
Trial of eicosapentaenoic acid on muscle stiffness
Japan |
muscle stiffness
Not applicable | Adult |
Others
NO
The purpose of this study is investigating the influence of eicosapentaenoic acid (EPA) for muscle muscle stiffness following eccentric contractions.
Efficacy
Confirmatory
Not applicable
After ingestion of tested materials for 8 weeks, subjects perform eccentric contraction (ECC) with elbow flexors. Before and after ECC,
1) muscle stiffness
2) range of motion
After ingestion of tested materials for 8 weeks, subjects perform eccentric contraction (ECC) with elbow flexors. Before and after ECC,
1) maximal isometric contraction torque
2) muscle soreness measured as a visual analog scale
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
Tested material: EPA-rich fish oil
Dosage: 2.4g/day
Duration: 8 weeks
Tested material: corn oil
Dosage: 2.4g/day
Duration: 8 weeks
18 | years-old | <= |
Not applicable |
Male
Healthy male subjects
Subjects with
/resistance training more than five times a week for a year /no resistance training or exercise during over a year /serious liver, kidney, heart, respiratory, endocrine or metabolic diseases/ scheduled for surgery during this study/ administration of regular medication/ regular administration of supplements which affect this study / food allergies/ participation of other clinical trial during this study/ restriction of exercise/ any reason in the opinion of the lead principal investigator not to take part in this study
24
1st name | Eisuke |
Middle name | |
Last name | Ochi |
Hosei University
Faculty of Bioscience
184-8584
3-7-2 Kajino-cho, Koganei, Tokyo, Japan
042-387-6337
ochi@hosei.ac.jp
1st name | Eisuke |
Middle name | |
Last name | Ochi |
Hosei University
Faculty of Bioscience
184-8584
3-7-2 Kajino-cho, Koganei, Tokyo, Japan
042-387-6337
ochi@hosei.ac.jp
Hosei University
Nippon Suisan Kaisha Ltd.
Profit organization
Japan
Research Ethics Committee of Hosei University Sports Research Center
4342 Aihara-cho, Machida, Tokyo, Japan
042-783-2732
tamatai@hosei.ac.jp
NO
法政大学生命科学部(東京都)
(Hosei Univesity Faculty of Bioscience)
2017 | Year | 07 | Month | 20 | Day |
https://jissn.biomedcentral.com
Published
https://jissn.biomedcentral.com
16
MVC torque and ROM were significantly higher in the EPA group than in the PL group after ECCs. Muscle soreness, upper arm circumference, and muscle echo intensity were significantly higher in the PL group than in the EPA group after ECCs. In addition, muscle stiffness at 150 deg was significantly higher in the PL group than in the EPA group immediately after ECCs.
2019 | Year | 04 | Month | 01 | Day |
Healthy men
Subjects consumed either EPA 600 mg and DHA 260 mg per day or placebo supplement for 8 weeks prior to exercise. Moreover, they performed six sets of 10 ECCs at 100% maximal voluntary contraction (MVC) using a dumbbell. Measuremetns were assessed before exercise; immediately after exercise; and 1, 2, and 5 days after exercise.
No events
Muscle torque, range of motion (ROM), upper arm circumference, muscle soreness, muscle echo intensity, and muscle stiffness
Main results already published
2017 | Year | 07 | Month | 10 | Day |
2017 | Year | 07 | Month | 07 | Day |
2017 | Year | 07 | Month | 20 | Day |
2017 | Year | 09 | Month | 22 | Day |
2017 | Year | 11 | Month | 23 | Day |
2017 | Year | 12 | Month | 30 | Day |
2018 | Year | 03 | Month | 31 | Day |
2017 | Year | 07 | Month | 10 | Day |
2020 | Year | 01 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032244
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