Unique ID issued by UMIN | UMIN000028739 |
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Receipt number | R000032889 |
Scientific Title | Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor- |
Date of disclosure of the study information | 2017/10/01 |
Last modified on | 2024/04/01 09:36:49 |
Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-
Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-
Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-
Clinical trial of prevention for PCI-related myocardial infarction evaluating index of microvascular resistance in stable coronary artery disease. -Effect of Fasudil, a selective Rho-kinase inhibitor-
Japan |
stable coronary artery disease
Cardiology |
Others
NO
The aim of this study is to adress wheter Fasudil, a selective Rho-kinase inhibitor, could prevent PCI-related myocardial infarction.
Efficacy
index of microvascular resistance
high sensitive troponin T
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Placebo
2
Prevention
Medicine |
intracoronary single administration of 30mg of Fasudil
intracoronary single administration of normal saline
20 | years-old | <= |
100 | years-old | > |
Male and Female
(1)stable coronary artery disease
(2)stenosis in left coronary artery
(3)pressure wire enable to pass the lesion
(4)20 years old and older
(5)male or female
(1) severe anemia or infection, malignancy, decompensated congestive heart failure
(2) previous myocardial infarction in the target vessel
(3) target vessel is a donar or recipient of collateral artery
(4)systolic blood pressure under 80mmHg
(5)bronchial asthma or allergy for adenosin triphosphate
(6) left main coronary trunk lesion or severe stenosis with contrast delay
(7) severe renal or liver dysfunction
(8) allergy for Fasudil
40
1st name | Hiroaki |
Middle name | |
Last name | Shimokawa |
Tohoku University
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
980-8574
1-1, Seiryouchou, Aobaku, Sendai City
022-7171-7153
shimo@cardio.med.tohoku.ac.jp
1st name | Yoku |
Middle name | |
Last name | Kikuchi |
Tohoku University
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
980-8574
1-1, Seiryouchou, Aobaku, Sendai City
022-717-7153
ykikuchi911@cardio.med.tohoku.ac.jp
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Other
Ethics Committee of Tohoku University Hospital
1-1, Seiryouchou, Aobaku, Sendai City
022-728-4105
rinri-2@proj.med.tohoku.ac.jp
NO
2017 | Year | 10 | Month | 01 | Day |
Unpublished
Open public recruiting
2010 | Year | 10 | Month | 01 | Day |
2017 | Year | 10 | Month | 04 | Day |
2017 | Year | 10 | Month | 04 | Day |
2025 | Year | 03 | Month | 31 | Day |
2025 | Year | 03 | Month | 31 | Day |
2017 | Year | 08 | Month | 18 | Day |
2024 | Year | 04 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000032889
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