Unique ID issued by UMIN | UMIN000028952 |
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Receipt number | R000033128 |
Scientific Title | Tailor-made chemotherapy based on biomarker for lung cancer and malignant mediastinal tumor |
Date of disclosure of the study information | 2017/09/02 |
Last modified on | 2019/09/04 19:46:55 |
Tailor-made chemotherapy based on biomarker for lung cancer and malignant mediastinal tumor
Tailor-made chemotherapy based on biomarker
Tailor-made chemotherapy based on biomarker for lung cancer and malignant mediastinal tumor
Tailor-made chemotherapy based on biomarker
Japan |
lung cancer, malignant mediastinal tumor
Chest surgery |
Malignancy
YES
Evaluation of chemotherapy-associated biomarkers in tumors for effective tailor-made chemotherapy
Efficacy
Confirmatory
Pragmatic
Not applicable
overall survival rate at 3 years after initial treatment
progression-free survival rate at 3 years after initial treatment
response rate
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Treatment
Other |
Tailor-made chemothrapy is performed for patients with advanced-stage cancer or reccurent tumor after surgery. The tailor-made chemothrapy is contined until detection of re-growth of tumors.
20 | years-old | <= |
80 | years-old | >= |
Male and Female
advanced stage lung cancer
advanced stage malignant mediastinal tumor
Patients not applicable for conventinal chemotherapy, due to leukocytopenia, thrombocytopenia, hepatic dysfunction, or renal dysfunction.
300
1st name | Cheng-long |
Middle name | |
Last name | Huang |
Kitano hospital
Department of Thoracic Surgery
530-8480
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
chuang@kitano-hp.or.jp
1st name | Cheng-long |
Middle name | |
Last name | Huang |
Kitano hospital
Department of Thoracic Surgery
530-8480
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
http://www.kitano-hp.or.jp/etcproject/kokyuki-center/kenkyu_kokyuki-center/index.html
chuang@kitano-hp.or.jp
Dapartment of Thoracic Surgery, Kitano hospital
Kitano hospital
Self funding
Kitano Hospital
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
chuang@kitano-hp.or.jp
NO
2017 | Year | 09 | Month | 02 | Day |
http://www.kitano-hp.or.jp/etcproject/kokyuki-center/kenkyu_kokyuki-center/index.html
Partially published
The reccurence-free survival rate was significantly higher in patients with class III-beta tubulin-low tumors and treated with taxane for postoperative adjuvant chemotherapy. Evaluation of intratumoral expression of class III-beta tubulin is usuful for selection of postoperative adjuvant chemotherapy(The 34th annual meeting of the Japanese-association for chest surgery, Fukuoka 2017.5.18.).
Enrolling by invitation
2011 | Year | 11 | Month | 16 | Day |
2011 | Year | 11 | Month | 16 | Day |
2011 | Year | 11 | Month | 17 | Day |
2031 | Year | 12 | Month | 31 | Day |
2017 | Year | 09 | Month | 01 | Day |
2019 | Year | 09 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000033128
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