Unique ID issued by UMIN | UMIN000028977 |
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Receipt number | R000033153 |
Scientific Title | Safety and efficacy in patients with uncontrolled asthma: systemitic review and meta-analysis |
Date of disclosure of the study information | 2017/09/04 |
Last modified on | 2017/09/03 08:40:41 |
Safety and efficacy in patients with uncontrolled asthma: systemitic review and meta-analysis
Anti-IL-13 therapies in uncontrolled asthma
Safety and efficacy in patients with uncontrolled asthma: systemitic review and meta-analysis
Anti-IL-13 therapies in uncontrolled asthma
Japan |
uncontrolled asthma
Pneumology |
Others
NO
To compare the efficacy and safety profiles between anti-IL-13 therapies and placebo in patients with uncontrolled asthma by performing a meta-analysis of RCTs.
Safety,Efficacy
chenge in FEV1.0
incidence of all adverse events
time to first asthma exacerbation
change in ACQ score
change in AQLQ
Others,meta-analysis etc
12 | years-old | <= |
75 | years-old | > |
Male and Female
RCTs that assessed the clinical efficacy and safety of anti-IL-13 therapies in adolescents or adults aged 12 years or older with a diagnosis of uncontrolled, severe, or moderate to severeasthma; and studies whose outcomes included pulmonary function, any adverse event, asthma exacerbation, asthma control, or asthma related quality of life.
Observational, case-control, cohort, and non-blinded clinical trials were excluded.
1000
1st name | |
Middle name | |
Last name | koichi ando |
Showa University
Division of Respiratory Medicine and Allergology, Department of Medicine
Hatanodai, 1-5-8, Shinagawa-ku, Tokyo, Japan
+81-3784-8532
koichi-a@med.showa-u.ac.jp
1st name | |
Middle name | |
Last name | Showa University |
Showa University
Division of Respiratory Medicine and Allergology, Department of Medicine
Hatanodai, 1-5-8, Shinagawa-ku, Tokyo, Japan
+81-3784-8532
koichi-a@med.showa-u.ac.jp
Showa University
Showa University
Other
NO
2017 | Year | 09 | Month | 04 | Day |
Unpublished
Completed
2017 | Year | 08 | Month | 03 | Day |
2017 | Year | 08 | Month | 05 | Day |
pulmonary function was significantly improved in the anti-IL-13 group compared with the placebo group, and that there was no significant differences in the incidences of all adverse events between the anti-IL-13 group and the placebo group. These results suggest that anti-IL-13 therapies, are effective and generally well-tolerated in patients with uncontrolled asthma.
2017 | Year | 09 | Month | 03 | Day |
2017 | Year | 09 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000033153
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